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CELF6 antibody (CUGBP, Elav-Like Family Member 6) (AA 53-82)

Details for Product anti-CELF6 Antibody No. ABIN950681, Supplier: Log in to see
Antigen
  • 6330569O16Rik
  • Brunol6
  • BRUNOL6
Epitope
AA 53-82, N-Term
16
15
2
1
1
1
1
Reactivity
Human, Mouse (Murine)
33
9
6
1
Host
Rabbit
32
1
Clonality
Polyclonal
Conjugate
This CELF6 antibody is un-conjugated
2
2
2
2
2
2
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
27
20
20
4
Supplier
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Immunogen KLH conjugated synthetic peptide between 53-82 amino acids from the N-terminal region of human BRUNOL6
Isotype Ig
Specificity This antibody reacts to BRUNOL6.
Cross-Reactivity (Details) Species reactivity (tested):Mouse.
Purification Affinity chromatography on Protein A
Alternative Name BRUNOL6 / CELF6 (CELF6 Antibody Abstract)
Background Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene.Synonyms: BRUNOL-6, Bruno-like protein 6, CELF-6, CUG-BP- and ETR-3-like factor 6
Gene ID 60677
NCBI Accession NP_001166155
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) sodium azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-CELF6 antibody (CUGBP, Elav-Like Family Member 6) (AA 53-82) (ABIN950681) BRUNOL6 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffi...
Western Blotting (WB) image for anti-CELF6 antibody (CUGBP, Elav-Like Family Member 6) (AA 53-82) (ABIN950681) BRUNOL6 Antibody (N-term) western blot analysis in mouse heart tissue lysates (35µg/l...
Background publications Ladd, Nguyen, Malhotra, Cooper: "CELF6, a member of the CELF family of RNA-binding proteins, regulates muscle-specific splicing enhancer-dependent alternative splicing." in: The Journal of biological chemistry, Vol. 279, Issue 17, pp. 17756-64, 2004 (PubMed).

Wistow, Bernstein, Wyatt, Fariss, Behal, Touchman, Bouffard, Smith, Peterson: "Expressed sequence tag analysis of human RPE/choroid for the NEIBank Project: over 6000 non-redundant transcripts, novel genes and splice variants." in: Molecular vision, Vol. 8, pp. 205-20, 2002 (PubMed).

Good, Chen, Warner, Herring: "A family of human RNA-binding proteins related to the Drosophila Bruno translational regulator." in: The Journal of biological chemistry, Vol. 275, Issue 37, pp. 28583-92, 2000 (PubMed).