Intercellular Adhesion Molecule 2 (ICAM2) (AA 191-218), (Middle Region) antibody

Details for Product No. ABIN951145
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Antigen
Synonyms ICAM2, CD102, Icam-2, Ly-60
Epitope
AA 191-218, Middle Region
(15), (10), (9), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(121), (77), (15)
Host
Rabbit
(66), (60), (56), (2)
Clonality
Polyclonal
Conjugate
Un-conjugated
(29), (24), (11), (4), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Flow Cytometry (FACS), ELISA, Western Blotting (WB)
(125), (55), (51), (44), (31), (25), (18), (11), (10), (6), (4), (3), (2), (2), (1), (1)
Pubmed 3 references available
Quantity 0.4 mL
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN951145
357.50 $
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  • +1 404 474 4654
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Immunogen KLH conjugated synthetic peptide between 191-218 amino acids from the Central region of human CD102 / ICAM2
Specificity This antibody recognizes Human CD102 / ICAM2 (Center).
Purification Protein A column, followed by peptide affinity purification
Alternative Name CD102 / ICAM2
Background The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. Several transcript variants encoding the same protein have been found for this gene.
Alternate names: ICAM-2, Intercellular adhesion molecule 2
Molecular Weight 30654 Da
Gene ID 3384
NCBI Accession NP_000864
Research Area CD Antigens, Surface Receptors of Immune Cells
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09% (w/v) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Davila, Froeling, Tan et al.: "New genetic associations detected in a host response study to hepatitis B vaccine." in: Genes and immunity, Vol. 11, Issue 3, pp. 232-8, 2010 (PubMed).

Rajaraman, Brenner, Neta et al.: "Risk of meningioma and common variation in genes related to innate immunity." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 19, Issue 5, pp. 1356-61, 2010 (PubMed).

Han, Lan, Park et al.: "Polymorphisms in innate immunity genes and risk of childhood leukemia." in: Human immunology, Vol. 71, Issue 7, pp. 727-30, 2010 (PubMed).

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