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CD103 antibody

ITGAE Reactivity: Human, Primate FACS, WB, IP, IHC (fro) Host: Mouse Monoclonal Ber-ACT8 unconjugated
Catalog No. ABIN951148
  • Target See all CD103 (ITGAE) Antibodies
    CD103 (ITGAE) (Integrin, alpha E (Antigen CD103, Human Mucosal Lymphocyte Antigen 1, alpha Polypeptide) (ITGAE))
    Reactivity
    • 68
    • 30
    • 5
    • 5
    • 4
    • 4
    Human, Primate
    Host
    • 41
    • 31
    • 14
    • 9
    • 4
    Mouse
    Clonality
    • 67
    • 32
    Monoclonal
    Conjugate
    • 42
    • 12
    • 10
    • 7
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    This CD103 antibody is un-conjugated
    Application
    • 49
    • 34
    • 23
    • 21
    • 19
    • 14
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Specificity
    This antibody recognizes CD103 (alpha E integrin), a type I transmembrane glycoprotein primarily found on intestinal intraepithelial lymphocytes.
    Cross-Reactivity (Details)
    Species reactivity (tested):Human, Non-Human Primates
    Purification
    Protein-A affinity chromatography
    Purity
    > 95 % pure by SDS-PAGE
    Immunogen
    HTLV-1 induced human T cell line MAPS16
    Clone
    Ber-ACT8
    Isotype
    IgG1
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    Discover our top product ITGAE Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 to -70 °C for longer.
  • Target
    CD103 (ITGAE) (Integrin, alpha E (Antigen CD103, Human Mucosal Lymphocyte Antigen 1, alpha Polypeptide) (ITGAE))
    Alternative Name
    CD103 (ITGAE Products)
    Synonyms
    A530055J10 antibody, CD103 antibody, aM290 antibody, alpha-E1 antibody, alpha-M290 antibody, HUMINAE antibody, integrin alpha E, epithelial-associated antibody, integrin subunit alpha E antibody, Itgae antibody, ITGAE antibody
    Background
    CD103 / Integrin alphaE is an integrin subunit that is expressed on intraepithelial lymphocytes, epithelial dendritic cells, lamina propria-derived dendritic cells, a subpopulation of lamina propria T cells, a small subset of peripheral lymphocytes, namely T reg cells, and on activated and TGF-beta stimulated lymphocytes. CD103 is in mature form cleaved into two disulfide-linked chains (C-terminal 150 kDa chain and N-terminal 25 kDa chain). It heterodimerizes with integrin beta7 subunit to form alphaE/beta7 integrin (mucosal lymphocyte 1 antigen), which through binding E-cadherin mediates homing of lymphocytes to the intestinal epithelium, and, in addition to the role in adhesion, may serve as an accessory molecule for intraepithelial lymphocyte activation.Synonyms: HML-1 antigen, ITGAE, Integrin alpha-E, Integrin alpha-IEL, Mucosal lymphocyte 1 antigen
    Gene ID
    3682
    NCBI Accession
    NP_002199
    UniProt
    P38570
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