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IL1R2 antibody (Middle Region)

IL1R2 Reactivity: Human WB, EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN951182
  • Target See all IL1R2 Antibodies
    IL1R2 (Interleukin 1 Receptor, Type II (IL1R2))
    Binding Specificity
    • 16
    • 8
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 273-300, Middle Region
    Reactivity
    • 70
    • 27
    • 20
    • 4
    Human
    Host
    • 49
    • 22
    • 1
    • 1
    Rabbit
    Clonality
    • 51
    • 21
    Polyclonal
    Conjugate
    • 40
    • 6
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IL1R2 antibody is un-conjugated
    Application
    • 60
    • 33
    • 30
    • 13
    • 13
    • 8
    • 7
    • 7
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Specificity
    This antibody recognizes CD121b / IL1R2.
    Cross-Reactivity (Details)
    Species reactivity (tested):Human
    Purification
    Purified through a Protein A column followed by peptide affinity purification
    Immunogen
    Synthetic peptide - KLH conjugated - corresponding to the central region (between 273-300aa) of human CD121b / IL1R2.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product IL1R2 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) Sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    IL1R2 (Interleukin 1 Receptor, Type II (IL1R2))
    Alternative Name
    CD121b / IL1R2 (IL1R2 Products)
    Synonyms
    CD121b antibody, CDw121b antibody, IL-1R-2 antibody, IL-1RT-2 antibody, IL-1RT2 antibody, IL1R2c antibody, IL1RB antibody, Il1r-2 antibody, IL-1R2 antibody, interleukin 1 receptor type 2 antibody, interleukin 1 receptor, type II antibody, interleukin-like antibody, IL1R2 antibody, Il1r2 antibody, KK34 antibody
    Background
    The protein encoded by the IL1R2 gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Two alternatively spliced transcript variants encoding the same protein have been reported.Synonyms: CD121 antigen-like family member B, CDw121b, IL-1R-2, IL-1R-beta, IL1RB, Interleukin-1 receptor type II
    Gene ID
    7850
    NCBI Accession
    NP_004624
    Pathways
    NF-kappaB Signaling
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