SLAMF1 antibody

Catalog No. ABIN951192

Product Details anti-SLAMF1 Antibody

Target: SLAMF1 (Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SLAMF1 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunofluorescence (IF)

Specificity: This Monoclonal SLAM.4 antibody recognizes CD150, a cell surface molecule expressed on lymphocytes and involved in their activation.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Protein A-affinity chromatography

Immunogen: Human CD150-transfected 300.19 cells

Clone: SLAM-4

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL (> 95% pure by SDS-PAGE)

Buffer: Azide free phosphate buffered saline (PBS), pH ~7.4, 0.2 μm filter sterilized

Preservative: Azide free

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Target Details for SLAMF1

Target: SLAMF1 (Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1))

Alternative Name: CD150 / SLAMF1 (SLAMF1 Products)

Synonyms: CD150 antibody, SLAM antibody, SLAMF1 antibody, 4933415F16 antibody, AA177906 antibody, CDw150 antibody, ESTM51 antibody, IPO-3 antibody, Slam antibody, RGD1560634 antibody, signaling lymphocytic activation molecule family member 1 antibody, SLAMF1 antibody, Slamf1 antibody

Background: CD150, also known as SLAM (signaling lymphocyte activation molecule) is a 70-95 kDa single chain transmembrane phosphoglycoprotein of the CD2 family. Its extracellular part contains eight potential N-glycosylation sites, and the intracellular tail contains three unique tyrosine-based motifs. These binding sites can be recognized by SH2-binding phosphatases and the adaptor proteins, such as SAP/SH2D1A or EAT-2. The SLAM family receptors are involved in leucocyte activation and contribute to the effective germinal center formation, generation of high-affinity antibody-secreting plasma cells, and memory T and B cells, thereby facilitating long-term immune response. CD150 expression is upregulated after cell activation.Synonyms: CDw150, Ipo-3, Signaling lymphocytic activation molecule, Slam

Gene ID: 6504

NCBI Accession: NP_003028

UniProt: Q13291