Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) (C-Term), (AA 189-219) antibody

Details for Product No. ABIN951195
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Antigen
Synonyms CTLA-4, CTLA4, CD152, Cd152, Ctla-4, Ly-56, CD, CELIAC3, GRD4, GSE, IDDM12, sCTLA4
Epitope
C-Term, AA 189-219
(35), (12), (8), (8), (7), (4), (4), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(126), (103), (74), (17), (17), (2)
Host
Rabbit
(101), (76), (58), (4), (1), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(27), (26), (20), (6), (4), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Application
Immunocytochemistry (ICC), Immunofluorescence (IF), ELISA, Western Blotting (WB)
(149), (70), (61), (34), (21), (20), (19), (15), (12), (11), (9), (2), (2), (1), (1)
Pubmed 1 reference available
Quantity 0.4 mL
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Catalog No. ABIN951195
357.50 $
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Immunogen KLH conjugated synthetic peptide between 189~219 amino acids from the C-terminal region of Human CTLA4. Genename: CTLA4
Specificity This antibody recognizes Human CD152 / CTLA4 (C-term).
Purification Affinity Chromatography on Protein A
Alternative Name CD152 / CTLA4
Background CTLA4 is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer
Alternate names: CTLA-4, Cytotoxic T-lymphocyte protein 4, Cytotoxic T-lymphocyte-associated antigen 4
Molecular Weight 24656 Da
Gene ID 1493
NCBI Accession NP_001032720
Research Area CD Antigens, Surface Receptors of Immune Cells
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS 0.09% Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Mosbruger, Duggal, Goedert et al.: "Large-scale candidate gene analysis of spontaneous clearance of hepatitis C virus." in: The Journal of infectious diseases, Vol. 201, Issue 9, pp. 1371-80, 2010 (PubMed).

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