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TNFSF4 antibody (Middle Region)
TNFSF4
Reactivity: Human
WB, EIA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-TNFSF4 Antibody
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Target
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TNFSF4
(Tumor Necrosis Factor (Ligand) Superfamily, Member 4 (TNFSF4))
Binding Specificity
All epitopes for TNFSF4 antibodies
AA 101-131, Middle Region
Reactivity
All reactivities for TNFSF4 antibodies
Human
Host
All hosts for TNFSF4 antibodies
Rabbit
Clonality
All clonalities for TNFSF4 antibodies
Polyclonal
Conjugate
All conjugates for TNFSF4 antibodies
This TNFSF4 antibody is un-conjugated
Application
All applications for TNFSF4 antibodies
Western Blotting (WB), Enzyme Immunoassay (EIA)
Specificity
This antibody detects CD252 / TNFSF4 (Center).
Cross-Reactivity (Details)
Species reactivity (tested):Human
Purification
Protein A column followed by peptide affinity purification
Immunogen
KLH conjugated synthetic peptide between 101-131 amino acids from the Central region of human TNFSF4
Isotype
Ig Fraction
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Discover our top product TNFSF4 Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
0.25 mg/mL
Buffer
PBS with 0.09 % (W/V) sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.
Target Details for TNFSF4
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Target
TNFSF4
(Tumor Necrosis Factor (Ligand) Superfamily, Member 4 (TNFSF4))
Alternative Name
CD252 / TNFSF4 (TNFSF4 Products )
Synonyms
TNFSF4 antibody, OX40L antibody, TNFRSF4 antibody, CD134L antibody, CD252 antibody, GP34 antibody, OX-40L antibody, OX4OL antibody, TXGP1 antibody, Ath-1 antibody, Ath1 antibody, Ox40l antibody, Txgp1l antibody, gp34 antibody, TNF superfamily member 4 antibody, tumor necrosis factor (ligand) superfamily, member 4 antibody, TNFSF4 antibody, Tnfsf4 antibody
Background
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF4/OX4. It is found to be involved in T cell antigen-presenting cell (APC) interactions. In surface Ig- and CD40-stimulated B cells, this cytokine along with CD70 has been shown to provide CD28-independent costimulatory signals to T cells. This protein and its receptor are reported to directly mediate adhesion of activated T cells to vascular endothelial cells.Synonyms: Glycoprotein Gp34, OX40 ligand, OX40L, TAX transcriptionally-activated glycoprotein 1, TXGP1, Tumor necrosis factor ligand superfamily member 4
Gene ID
7292
NCBI Accession
NP_003317
Pathways
Cellular Response to Molecule of Bacterial Origin , Regulation of Leukocyte Mediated Immunity , Positive Regulation of Immune Effector Process , Production of Molecular Mediator of Immune Response , Activated T Cell Proliferation , Cancer Immune Checkpoints
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