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CD27 antibody (PE)

CD27 Reactivity: Mouse FACS, IHC (fro), Func Host: Hamster Monoclonal LG-3A10 PE
Catalog No. ABIN951257
  • Target See all CD27 Antibodies
    CD27 (CD27 Molecule (CD27))
    Reactivity
    • 168
    • 51
    • 37
    • 6
    • 6
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Mouse
    Host
    • 104
    • 77
    • 14
    • 3
    • 2
    • 1
    Hamster
    Clonality
    • 111
    • 88
    • 2
    Monoclonal
    Conjugate
    • 72
    • 20
    • 19
    • 12
    • 8
    • 7
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD27 antibody is conjugated to PE
    Application
    • 128
    • 79
    • 50
    • 29
    • 29
    • 17
    • 16
    • 13
    • 13
    • 12
    • 10
    • 6
    • 5
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    • 2
    • 2
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    • 1
    • 1
    Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)
    Specificity
    This Monoclonal Antibody is specific for the Mouse CD27 receptor.
    Immunogen
    MCD27 tag expressing clones AR0524 and AR0530 Donor: Armenian hamster spleen Fusion Partner: SP2/0 Murine Myeloma Partner
    Clone
    LG-3A10
    Isotype
    IgG1
    Top Product
    Discover our top product CD27 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    0,1 mg/mL
    Buffer
    PBS, 0.02 % Sodium Azide, EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/mL
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    DO NOT FREEZE!
    Storage
    4 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C.
  • Target
    CD27 (CD27 Molecule (CD27))
    Alternative Name
    CD27 (CD27 Products)
    Synonyms
    TNFRSF7 antibody, S152 antibody, Tnfrsf7 antibody, Tp55 antibody, S152. LPFS2 antibody, T14 antibody, CD27 molecule antibody, CD27 antigen antibody, CD27 antibody, Cd27 antibody
    Background
    CD27 is part of the Tumor Necrosis Factor (TNF) family of receptors and is lymphocyte specific. Murine CD27 is expressed on the great majority of both αβ and γδ T lymphocytes, on a small population of peripheral B cells and on a very small subset of B220+ cells in the bone marrow. Murine CD27 is found on all thymocytes except a subset of CD4-CD8-precursors. There are two known basic functions of CD27 signaling. First, the binding of CD27 to CD70, a protein which is also expressed in T and B cells, provides costimulatory signals in lymphocyte proliferation and immunoglobulin production. Second, the association of CD27 with intracellular Siva, a proapoptotic protein, results in the induction of apoptotic events.Synonyms: CD27L receptor, T-cell activation antigen CD27, T14, TNFRSF7, Tumor necrosis factor receptor superfamily member 7
    Gene ID
    21940
    NCBI Accession
    NP_001028298
    UniProt
    P41272
    Pathways
    Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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