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IGSF8 antibody (Middle Region)

IGSF8 Reactivity: Human, Mouse WB, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN951296
  • Target See all IGSF8 Antibodies
    IGSF8 (Immunoglobulin Superfamily, Member 8 (IGSF8))
    Binding Specificity
    • 16
    • 11
    • 7
    • 7
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 233-262, Middle Region
    Reactivity
    • 43
    • 37
    • 7
    • 7
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 42
    • 8
    Rabbit
    Clonality
    • 43
    • 7
    Polyclonal
    Conjugate
    • 18
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IGSF8 antibody is un-conjugated
    Application
    • 42
    • 24
    • 22
    • 15
    • 13
    • 13
    • 6
    • 5
    • 3
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificity
    This antibody detects IGSF8 (Center).
    Cross-Reactivity (Details)
    Species reactivity (tested):Human, Mouse
    Purification
    Purified through a protein A column; followed by peptide affinity purification.
    Immunogen
    Synthetic peptide (233-262 aa) - KLH conjugated - corresponding to internal domain of human IGSF8.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product IGSF8 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) Sodium Azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    IGSF8 (Immunoglobulin Superfamily, Member 8 (IGSF8))
    Alternative Name
    CD316 / IGSF8 (IGSF8 Products)
    Synonyms
    MGC77222 antibody, IGSF8 antibody, MGC151661 antibody, CD316 antibody, CD81P3 antibody, EWI-2 antibody, EWI2 antibody, KCT-4 antibody, LIR-D1 antibody, PGRL antibody, AA033172 antibody, AU041109 antibody, ESTM34 antibody, R75384 antibody, immunoglobulin superfamily, member 8 antibody, immunoglobulin superfamily member 8 antibody, igsf8 antibody, IGSF8 antibody, Igsf8 antibody
    Background
    GSF8/PGRL/EWI-2 is a membrane protein that contains 4 Ig domains and forms highly proximal, specific and stoichiometric complexes with both CD9 and CD81 a tetraspanin. Tetraspanins and their molecular partners from primary complexes that then undergo tetraspanin-tetraspanin interactions to form a network of molecular interactions call a tetraspanin web. IGSF8 then may play a key role in diverse functions ascribed to CD81 and CD9 including oocyte fertilization or hepatitis C virus function, regulation of proliferation and differentiation of keratinocytes. It may also be a negative regulator of cell motility and suppress T-cell mobility coordinately with CD81.Synonyms: CD81 partner 3, CD81P3, EWI2, Glu-Trp-Ile EWI motif-containing protein 2, Immunoglobulin superfamily member 8, KCT4, Keratinocytes-associated transmembrane protein 4, LIR-D1
    Gene ID
    93185
    NCBI Accession
    NP_001193594
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