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ITGA4 antibody (PE)

ITGA4 Reactivity: Mouse FACS Host: Rat Monoclonal R1-2 PE

Catalog No. ABIN951339

Datasheet as PDF

Target See all ITGA4 Antibodies

ITGA4 (Integrin alpha 4 (ITGA4))
Reactivity
134

91

35

19

13

9

8

7

7

7

4

4

2

2

2

1

1

1

1

1

1

1

1
Mouse
Host
80

50

35
Rat
Compatible Secondaries
Clonality
97

70

1
Monoclonal
Conjugate
78

16

14

11

6

4

4

3

3

3

3

3

3

2

2

2

2

1

1

1

1

1

1

1

1

1

1
This ITGA4 antibody is conjugated to PE
Application
100

59

39

33

27

22

13

11

10

4

3

3

3

2

2

2

1

1

1
Flow Cytometry (FACS)

Specificity

This CD49d Monoclonal Antibody reacts with Alpha-4 integrin (CD49d/ITGA4).

Purification

Protein G Chromatography

Immunogen

Peyers Patch HEV binding lymphoma line (TK1). Donor: Fisher Spleen. Fusion Partner: P3x63Ag8.653.

Clone

R1-2

Isotype

IgG2b

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ITGA4 Reactivity: Human FACS, WB, ELISA Host: Mouse Monoclonal 5C4 unconjugated

anti-Integrin alpha 4 (ITGA4) (AA 551-650) antibody
ITGA4 Reactivity: Human, Mouse, Rabbit FACS, WB, ELISA, IHC (p) Host: Rabbit Polyclonal unconjugated

anti-Integrin alpha 4 (ITGA4) (AA 833-977) antibody
ITGA4 Reactivity: Human FACS, WB, IHC, ELISA, ICC, Neut Host: Mouse Monoclonal 7E4C5 unconjugated

anti-Integrin alpha 4 (ITGA4) (AA 376-558) antibody
ITGA4 Reactivity: Human IHC, ELISA, IF Host: Rabbit Polyclonal unconjugated

anti-Integrin alpha 4 (ITGA4) (C-Term) antibody
ITGA4 Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated

anti-Integrin alpha 4 (ITGA4) antibody
ITGA4 Reactivity: Human FACS, WB, EIA Host: Mouse Monoclonal 5C4 unconjugated

anti-Integrin alpha 4 (ITGA4) antibody
ITGA4 Reactivity: Mouse FACS, IP, IHC (fro) Host: Rat Monoclonal R1-2 unconjugated

anti-Integrin alpha 4 (ITGA4) antibody
ITGA4 Reactivity: Mouse FACS, IP, IHC (fro) Host: Rat Monoclonal DATK32 unconjugated

anti-Integrin alpha 4 (ITGA4) antibody
ITGA4 Reactivity: Mouse FACS, IP, IHC (fro), Func Host: Rat Monoclonal DATK32 unconjugated

Application Notes

Optimal working dilution should be determined by the investigator.

Restrictions

For Research Use only
Concentration

0.1 mg/mL

Buffer

PBS containing 0.02 % Sodium Azide as preservative and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/mL

Preservative

Sodium azide

Precaution of Use

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage

4 °C

Storage Comment

Store the antibody undiluted at 2-8 °C. DO NOT FREEZE!
Target

ITGA4 (Integrin alpha 4 (ITGA4))

Alternative Name

CD49d / ITGA4 (ITGA4 Products)

Synonyms

CD49D antibody, IA4 antibody, LOC100219853 antibody, integrin subunit alpha 4 antibody, integrin alpha 4 antibody, integrin subunit alpha 4 S homeolog antibody, ITGA4 antibody, Itga4 antibody, itga4.S antibody

Background

CD49d helps to mediate cell-cell and cell-matrix interactions. Alpha-4 integrin combines with b1 and b7 integrin to form VLA-4 and LPAM-1 (Peyers patch homing receptor) respectively. VLA-4 is expressed on most peripheral lymphocytes, thymocytes and monocytes. LPAM-1 is found on peripheral lymphocytes, but few thymocytes. Fibronectin and VCAM-1 act as ligands for both VLA-4 and LPAM-1. LPAM-1 also binds the mucosal vascular addressin MAdCAM-1. (1)Synonyms: CD49 antigen-like family member D, Integrin alpha-4, Integrin alpha-IV, VLA-4, VLA4

Gene ID

16401

NCBI Accession

NP_034706

UniProt

Q00651

Pathways

Integrin Complex