Leukocyte Immunoglobulin-Like Receptor, Subfamily A (With TM Domain), Member 5 (LILRA5) (N-Term), (AA 63-93) antibody

Details for Product No. ABIN951416
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Antigen
Synonyms E030017K20, EG232801, Gm4878, Lilrc1, CD85m, ILT10, LILRA5, CD85, CD85F, ILT-11, ILT11, LILRB7, LIR-9, LIR9
Epitope
N-Term, AA 63-93
(10), (7), (2), (2), (2), (1)
Reactivity
Human
(15), (3), (1)
Host
Rabbit
(15), (2), (1), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (2), (1), (1), (1), (1)
Application
ELISA, Western Blotting (WB)
(15), (11), (3), (1)
Pubmed 2 references available
Quantity 0.4 mL
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Catalog No. ABIN951416
357.50 $
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Immunogen KLH conjugated synthetic peptide between 63-93 amino acids from the N-terminal region of Human CD85f / LILRA5.
Specificity This antibody recognizes Human CD85f / LILRA5 (N-term).
Purification Protein A column, followed by peptide affinity purification
Alternative Name CD85f / LILRA5
Background The protein encoded by this gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family. LIR family members are known to have activating and inibitory functions in leukocytes. Crosslink of this receptor protein on the surface of monocytes has been shown to induce calcium flux and secretion of several proinflammatory cytokines, which suggests the roles of this protein in triggering innate immune responses. This gene is one of the leukocyte receptor genes that form a gene cluster on the chromosomal region 19q13.4. Four alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq].
Alternate names: CD85 antigen-like family member F, ILT-11, ILT11, Immunoglobulin-like transcript 11, LILRA5, LILRB7, LIR-9, LIR9, Leukocyte immunoglobulin-like receptor 9, Leukocyte immunoglobulin- like receptor subfamily A member 5
Molecular Weight 32755 Da
Gene ID 353514
NCBI Accession NP_067073
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09% (w/v) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Jones, Roghanian, Brown et al.: "Alternative mRNA splicing creates transcripts encoding soluble proteins from most LILR genes." in: European journal of immunology, Vol. 39, Issue 11, pp. 3195-206, 2010 (PubMed).

Mosbruger, Duggal, Goedert et al.: "Large-scale candidate gene analysis of spontaneous clearance of hepatitis C virus." in: The Journal of infectious diseases, Vol. 201, Issue 9, pp. 1371-80, 2010 (PubMed).

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