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Leukocyte Immunoglobulin-Like Receptor, Subfamily A (With TM Domain), Member 5 (LILRA5) (AA 63-93), (N-Term) antibody

Details for Product No. ABIN951416, Supplier: Log in to see
Antigen
  • E030017K20
  • EG232801
  • Gm4878
  • Lilrc1
  • CD85m
  • ILT10
  • LILRA5
  • CD85
  • CD85F
  • ILT-11
  • ILT11
  • LILRB7
  • LIR-9
  • LIR9
Epitope
N-Term, AA 63-93
19
15
2
2
2
1
1
Reactivity
Human
30
3
1
Host
Rabbit
29
2
2
1
Clonality
Polyclonal
Conjugate
Un-conjugated
4
3
2
2
2
2
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
26
22
4
1
Supplier
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Immunogen KLH conjugated synthetic peptide between 63-93 amino acids from the N-terminal region of Human CD85f / LILRA5.
Isotype Ig
Specificity This antibody recognizes Human CD85f / LILRA5 (N-term).
Purification Protein A column, followed by peptide affinity purification
Alternative Name CD85f / LILRA5 (LILRA5 Antibody Abstract)
Background The protein encoded by this gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family. LIR family members are known to have activating and inibitory functions in leukocytes. Crosslink of this receptor protein on the surface of monocytes has been shown to induce calcium flux and secretion of several proinflammatory cytokines, which suggests the roles of this protein in triggering innate immune responses. This gene is one of the leukocyte receptor genes that form a gene cluster on the chromosomal region 19q13.4. Four alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq].Synonyms: CD85 antigen-like family member F, ILT-11, ILT11, Immunoglobulin-like transcript 11, LILRA5, LILRB7, LIR-9, LIR9, Leukocyte immunoglobulin-like receptor 9, Leukocyte immunoglobulin-like receptor subfamily A member 5
Molecular Weight 32755 Da
Gene ID 353514
NCBI Accession NP_067073
Pathways
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-Leukocyte Immunoglobulin-Like Receptor, Subfamily A (With TM Domain), Member 5 (LILRA5) (AA 63-93), (N-Term) antibody (ABIN951416) Western blot analysis of CD85f / LILRA5 Antibody (N-term) in MDA-MB435 cell line lysa...
Background publications Mosbruger, Duggal, Goedert et al.: "Large-scale candidate gene analysis of spontaneous clearance of hepatitis C virus." in: The Journal of infectious diseases, Vol. 201, Issue 9, pp. 1371-80, 2010 (PubMed).

Jones, Roghanian, Brown et al.: "Alternative mRNA splicing creates transcripts encoding soluble proteins from most LILR genes." in: European journal of immunology, Vol. 39, Issue 11, pp. 3195-206, 2010 (PubMed).

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