Complement Component 5a Receptor 1 (C5AR1) (AA 178-205), (Middle Region) antibody

Details for Product No. ABIN951423
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Antigen
Synonyms C5AR1, C5R1, GPR77, C5aR, C5r1, Cd88, D7Msu1, C5A, C5AR, CD88
Epitope
AA 178-205, Middle Region
(13), (10), (10), (9), (8), (7), (6), (5), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(104), (59), (28), (17), (13), (13), (13), (6), (2)
Host
Rabbit
(58), (57), (52), (2)
Clonality
Polyclonal
Conjugate
Un-conjugated
(26), (11), (9), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Western Blotting (WB)
(119), (58), (36), (33), (19), (18), (17), (10), (8), (6), (6), (4), (4), (3), (2), (2), (2), (1), (1)
Pubmed 5 references available
Quantity 0.4 mL
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN951423
357.50 $
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Immunogen KLH conjugated synthetic peptide between 178-205 amino acids from the Central region of human C5AR1
Isotype Ig
Specificity This antibody reacts to CD88.
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Affinity chromatography on Protein A
Alternative Name CD88 / C5R1
Background Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production.Synonyms: C5AR1, C5a anaphylatoxin chemotactic receptor, C5a-R, C5aR, Complement Component 5a Receptor 1
Gene ID 728
NCBI Accession NP_001727
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) sodium azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Background publications Rajaraman, Brenner, Neta et al.: "Risk of meningioma and common variation in genes related to innate immunity." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 19, Issue 5, pp. 1356-61, 2010 (PubMed).

Han, Lan, Park et al.: "Polymorphisms in innate immunity genes and risk of childhood leukemia." in: Human immunology, Vol. 71, Issue 7, pp. 727-30, 2010 (PubMed).

Nishiura, Tokita, Li et al.: "The role of the ribosomal protein S19 C-terminus in Gi protein-dependent alternative activation of p38 MAP kinase via the C5a receptor in HMC-1 cells." in: Apoptosis : an international journal on programmed cell death, Vol. 15, Issue 8, pp. 966-81, 2010 (PubMed).

Skeie, Fingert, Russell et al.: "Complement component C5a activates ICAM-1 expression on human choroidal endothelial cells." in: Investigative ophthalmology & visual science, Vol. 51, Issue 10, pp. 5336-42, 2010 (PubMed).

Marc, Kristan, Rozman et al.: "Complement factor C5a in acute exacerbation of Chronic Obstructive Pulmonary Disease." in: Scandinavian journal of immunology, Vol. 71, Issue 5, pp. 386-91, 2010 (PubMed).

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