CEP164 antibody (N-Term)

Catalog No. ABIN951457

Product Details anti-CEP164 Antibody

Target: CEP164 (Centrosomal Protein 164kDa (CEP164))

Binding Specificity: AA 246-274, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CEP164 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Specificity: This antibody reacts to CE164.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 246-274 amino acids from the N-terminal region of human CE164

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for CEP164

Target: CEP164 (Centrosomal Protein 164kDa (CEP164))

Alternative Name: CEP164 (CEP164 Products)

Synonyms: AI450905 antibody, BC027092 antibody, D030051D21 antibody, mKIAA1052 antibody, RGD1560988 antibody, RGD1561243 antibody, NPHP15 antibody, centrosomal protein 164 antibody, CEP164 antibody, Cep164 antibody

Background: Plays a role in microtubule organization and/or maintenance for the formation of primary cilia (PC), a microtubule-based structure that protrudes from the surface of epithelial cells. Plays a critical role in G2/M checkpoint and nuclear divisions. A key player in the DNA damage-activated ATR/ATM signaling cascade since it is required for the proper phosphorylation of H2AX, RPA,CHK2 and CHK1. Plays a critical role in chromosome segregation, acting as a mediator required for the maintenance of genomic stability through modulation of MDC1, RPA and CHK1.Synonyms: Centrosomal protein of 164 kDa, KIAA1052

Molecular Weight: 164314 Da

Gene ID: 22897

NCBI Accession: NP_055771

Pathways: M Phase