CES2 (AA 343-373), (Middle Region) antibody

Details for Product No. ABIN951482, Supplier: Log in to see
Antigen
  • CE-2
  • CES2A1
  • PCE-2
  • iCE
  • Ces2
  • ces2A3
  • EG436059
  • Gm5744
  • carboxylesterase 2
  • carboxylesterase 2C
  • carboxylesterase 2H
  • CES2
  • Ces2
  • Ces2c
  • Ces2h
Epitope
AA 343-373, Middle Region
14
11
11
9
8
7
7
5
5
3
2
2
1
1
1
1
1
1
1
1
1
Reactivity
Human
87
15
7
4
1
1
Host
Rabbit
70
21
4
1
Clonality
Polyclonal
Conjugate
Un-conjugated
3
3
3
3
3
3
Application
Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
88
53
45
16
16
13
6
5
1
1
Options
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Immunogen KLH conjugated synthetic peptide between 343-373 amino acids from the Central region of human CES2
Isotype Ig
Specificity This antibody reacts to CES2.
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Affinity chromatography on Protein A
Alternative Name CES2 / ICE
Background CES2 is a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. The protein encoded by this gene is the major intestinal enzyme and functions in intestine drug clearance.Synonyms: CE-2, Carboxylesterase 2, hCE-2
Molecular Weight 61807 Da
Gene ID 8824
NCBI Accession NP_003860
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS, 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Flow Cytometry (FACS) image for anti-CES2 (AA 343-373), (Middle Region) antibody (ABIN951482) CES2 Antibody (Center) flow cytometric analysis of MCF-7 cells (right histogram...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-CES2 (AA 343-373), (Middle Region) antibody (ABIN951482) CES2 antibody (Center) immunohistochemistry analysis in formalin fixed and para...
Western Blotting (WB) image for anti-CES2 (AA 343-373), (Middle Region) antibody (ABIN951482) CES2 Antibody (Center) western blot analysis in MCF-7 cell line lysates (35µg/l...
Background publications Howard, Hsu, Grzywacz, Chen, Quandt, Vallejos, Whalley, Cui, Padilla, Arcury: "Evaluation of candidate genes for cholinesterase activity in farmworkers exposed to organophosphorus pesticides: association of single nucleotide polymorphisms in BCHE." in: Environmental health perspectives, Vol. 118, Issue 10, pp. 1395-9, 2010 (PubMed).

Hatfield, Tsurkan, Hyatt, Yu, Edwards, Hicks, Wadkins, Potter: "Biochemical and molecular analysis of carboxylesterase-mediated hydrolysis of cocaine and heroin." in: British journal of pharmacology, Vol. 160, Issue 8, pp. 1916-28, 2010 (PubMed).

Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010 (PubMed).

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