CHD1L antibody (Middle Region)

Catalog No. ABIN951497

Product Details anti-CHD1L Antibody

Target: CHD1L (Chromodomain Helicase DNA Binding Protein 1-Like (CHD1L))

Binding Specificity: AA 560-590, Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHD1L antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody reacts to CHD1L.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 560-590 amino acids from the Central region of human CHD1L

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for CHD1L

Target: CHD1L (Chromodomain Helicase DNA Binding Protein 1-Like (CHD1L))

Alternative Name: CHD1L (CHD1L Products)

Synonyms: CHD1L antibody, ALC1 antibody, CHDL antibody, 4432404A22Rik antibody, Alc1 antibody, Snf2p antibody, zgc:56084 antibody, chromodomain helicase DNA binding protein 1 like antibody, chromodomain helicase DNA binding protein 1-like antibody, CHD1L antibody, chd1l antibody, Chd1l antibody

Background: In response to DNA strand breaks, chromatin adopts a relaxed structure due to the addition of poly(ADP-ribose) (PAR) to chromatin proteins by PARP enzymes (see PARP1, MIM 173870), and this relaxation facilitates the repair of DNA damage. CHD1L interacts with PAR and has a role in chromatin relaxation following DNA damage (Ahel et al., 2009 [PubMed 19661379]).[supplied by OMIM].Synonyms: ALC1, Amplified in liver cancer protein 1, Chromodomain-helicase-DNA-binding protein 1-like

Molecular Weight: 78kd Isoform 3. 100984 Da

Gene ID: 9557

NCBI Accession: NP_004275