Claudin 22 (CLDN22) (AA 97-126), (Middle Region) antibody

Catalog No. ABIN951558

Product Details

Target: Claudin 22 (CLDN22)

Binding Specificity: AA 97-126, Middle Region

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes CLDN22 (Center).

Cross-Reactivity (Details): Species reactivity (tested):Human and Mouse.

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 97-126 amino acids from the Central region of human CLDN22

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details

Target: Claudin 22 (CLDN22)

Alternative Name: CLDN22 (CLDN22 Products)

Synonyms: CLDN21 antibody, 2210404A22Rik antibody, 5330431C14Rik antibody, 9530051B05Rik antibody, CLDN22 antibody, claudin 22 antibody, claudin-22 antibody, CLDN22 antibody, Cldn22 antibody, LOC102186369 antibody

Background: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is intronless and overlaps the 3' UTR of the WWC2 gene (GeneID: 80014) on the opposite strand.Synonyms: Claudin-22

Molecular Weight: 24509 Da

Gene ID: 53842

NCBI Accession: NP_001104789

Pathways: Cell-Cell Junction Organization, Hepatitis C