CLEC12B antibody (C-Type Lectin Domain Family 12, Member B) (AA 245-276)

Details for Product anti-CLEC12B Antibody No. ABIN951562, Supplier: Log in to see
Antigen
  • RGD1560487
  • UNQ5782
  • 4933425B16Rik
  • C-type lectin domain family 12, member B
  • Clec12b
  • CLEC12B
Epitope
AA 245-276, C-Term
14
11
5
Reactivity
Human, Mouse (Murine)
21
12
Host
Rabbit
21
Clonality
Polyclonal
Conjugate
This CLEC12B antibody is un-conjugated
2
2
2
2
2
2
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
18
15
14
6
Options
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Immunogen KLH conjugated synthetic peptide between 245-276 amino acids from the C-terminal region of human CLEC12B
Isotype Ig
Specificity This antibody reacts to CLEC12B.
Cross-Reactivity (Details) Species reactivity (tested):Human and Mouse.
Purification Affinity chromatography on Protein A
Alternative Name CLEC12B (CLEC12B Antibody Abstract)
Background Cell surface receptor that protects target cells against natural killer cell-mediated lysis. Modulates signaling cascades and mediates tyrosine phosphorylation of target MAP kinases.Synonyms: C-type lectin domain family 12 member B
Molecular Weight 31616 Da
Gene ID 387837
NCBI Accession NP_001123470
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS, 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-CLEC12B antibody (C-Type Lectin Domain Family 12, Member B) (AA 245-276) (ABIN951562) CLEC12B Antibody (C-term) immunohistochemistry analysis in formalin fixed and p...
Western Blotting (WB) image for anti-CLEC12B antibody (C-Type Lectin Domain Family 12, Member B) (AA 245-276) (ABIN951562) CLEC12B Antibody (C-term) western blot analysis in K562 cell line lysates (35µg...
Western Blotting (WB) image for anti-CLEC12B antibody (C-Type Lectin Domain Family 12, Member B) (AA 245-276) (ABIN951562) CLEC12B Antibody (C-term) western blot analysis in mouse testis tissue lysates ...
Background publications Hoffmann, Schellack, Textor, Konold, Schmitz, Cerwenka, Pflanz, Watzl: "Identification of CLEC12B, an inhibitory receptor on myeloid cells." in: The Journal of biological chemistry, Vol. 282, Issue 31, pp. 22370-5, 2007 (PubMed).

Clark, Gurney, Abaya, Baker, Baldwin, Brush, Chen, Chow, Chui, Crowley, Currell, Deuel, Dowd, Eaton, Foster, Grimaldi, Gu, Hass, Heldens, Huang, Kim, Klimowski, Jin, Johnson, Lee, Lewis, Liao, Mark et al.: "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. ..." in: Genome research, Vol. 13, Issue 10, pp. 2265-70, 2003 (PubMed).