IREM1 antibody (N-Term)

Catalog No. ABIN951573

Product Details anti-IREM1 Antibody

Target: IREM1 (Immune Receptor Expressed On Myeloid Cells 1 (IREM1))

Binding Specificity: AA 63-92, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IREM1 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody reacts to CLM1.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 63~92 amino acids from the N-terminal region of human CLM1

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for IREM1

Target: IREM1 (Immune Receptor Expressed On Myeloid Cells 1 (IREM1))

Alternative Name: CLM1 (IREM1 Products)

Synonyms: CLIM1 antibody, CLM-1 antibody, CLM1 antibody, Digr2 antibody, F730004D16Rik antibody, IREM1 antibody, IgSF13 antibody, LMIR3 antibody, Pigr3 antibody, CD300f antibody, RGD1309733 antibody, IREM-1 antibody, NKIR antibody, CD300 molecule like family member F antibody, Cd300 molecule-like family member F antibody, CD300 molecule like family member f antibody, Cd300lf antibody, CD300LF antibody

Background: CLM1 is an inhibitory receptor of the Ig superfamily expressed on myeloid cells. It mediates negative regulatory signals by recruiting SHP1 (PTPN6, MIM 176883) or SHIP.Synonyms: CD300 antigen-like family member F, CD300F, CD300LF, CD_antigen=CD300f, CLM-1, CMRF35-like molecule 1, Flags: Precursor, IGSF13, IREM-1, IREM1, IgSF13, Immune receptor expressed on myeloid cells 1, Immunoglobulin superfamily member 13, NK inhibitory receptor, NKIR, UNQ3105/PRO10111

Molecular Weight: 32335 Da

Gene ID: 146722

NCBI Accession: NP_620587