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Component of Oligomeric Golgi Complex 3 (COG3) (AA 673-703), (C-Term) antibody

Details for Product No. ABIN951616, Supplier: Log in to see
Antigen
  • CG 3248
  • CG3248
  • COG3
  • dCOG3
  • Dmel\\CG3248
  • E430004N23
  • SEC34
Epitope
C-Term, AA 673-703
16
15
2
2
2
2
1
1
Reactivity
Human
30
5
5
Host
Rabbit
24
6
Clonality
Polyclonal
Conjugate
Un-conjugated
2
2
2
2
2
2
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
27
22
5
1
Supplier
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Immunogen KLH conjugated synthetic peptide between 673-703 amino acids from the C-terminal region of human COG3.
Isotype Ig
Specificity This antibody reacts to COG3.
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Affinity chromatography on Protein A
Alternative Name COG3 (COG3 Antibody Abstract)
Background The protein encoded by this gene has similarity to a yeast protein. It seems to be part of a peripheral membrane protein complex localized on cis/medial Golgi cisternae where it may participate in tethering intra-Golgi transport vesicles. [provided by RefSeq].Synonyms: COG complex subunit 3, Component of oligomeric Golgi complex 3, Conserved oligomeric Golgi complex subunit 3, SEC34, Vesicle-docking protein SEC34 homolog, p94
Molecular Weight 94096 Da
Gene ID 83548
NCBI Accession NP_001191405
Research Area Signaling, Organelles
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS, 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-Component of Oligomeric Golgi Complex 3 (COG3) (AA 673-703), (C-Term) antibody (ABIN951616) COG3 Antibody (C-term) western blot analysis in Hela cell line lysates (35µg/la...
Background publications Laufman, Kedan, Hong, Lev: "Direct interaction between the COG complex and the SM protein, Sly1, is required for Golgi SNARE pairing." in: The EMBO journal, Vol. 28, Issue 14, pp. 2006-17, 2009

Shestakova, Zolov, Lupashin: "COG complex-mediated recycling of Golgi glycosyltransferases is essential for normal protein glycosylation." in: Traffic (Copenhagen, Denmark), Vol. 7, Issue 2, pp. 191-204, 2006

Loh, Hong: "The binary interacting network of the conserved oligomeric Golgi tethering complex." in: The Journal of biological chemistry, Vol. 279, Issue 23, pp. 24640-8, 2004

Dunham, Matthews, Burton, Ashurst, Howe, Ashcroft, Beare, Burford, Hunt, Griffiths-Jones, Jones, Keenan, Oliver, Scott, Ainscough, Almeida, Ambrose, Andrews, Ashwell, Babbage, Bagguley, Bailey et al.: "The DNA sequence and analysis of human chromosome 13. ..." in: Nature, Vol. 428, Issue 6982, pp. 522-8, 2004

Gevaert, Goethals, Martens, Van Damme, Staes, Thomas, Vandekerckhove: "Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides." in: Nature biotechnology, Vol. 21, Issue 5, pp. 566-9, 2003