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Cytoplasmic Polyadenylation Element Binding Protein 3 (CPEB3) (AA 314-343), (Middle Region) antibody

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AA 314-343, Middle Region
(14), (14), (8), (2), (2), (2), (1), (1)
(40), (19), (19), (1), (1), (1)
(37), (3)
(3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Enzyme Immunoassay (EIA), Western Blotting (WB)
(24), (18), (11), (4), (4)
Pubmed 3 references available
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Quantity 0.4 mL
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Immunogen KLH conjugated synthetic peptide between 314-343 amino acids from the Central region of Human CPEB3. Genename: CPEB3
Isotype Ig
Specificity This antibody recognizes Human CPEB3 (Center).
Purification Affinity Chromatography on Protein A
Alternative Name CPEB3 (CPEB3 Antibody Abstract)
Background Cytoplasmic polyadenylation element-binding (CPEB) proteins control polyadenylation-induced translation in early development. Studies in oocytes led to the delineation of Xenopus CPEB, the first member of the family to be identified, and its mouse homologue mCPEB-1. Recently, a second mouse family member, mCPEB-2, has been described in germ cells. Increasing evidence also implicates CPEB proteins as being important in the hippocampus, where these proteins are thought to regulate local protein synthesis and synaptic plasticity.Synonyms: CPE-BP3, CPE-binding protein 3, Cytoplasmic polyadenylation element-binding protein 3, KIAA0940, hCPEB-3
Molecular Weight 76014 Da
Gene ID 22849
NCBI Accession NP_001171608
Research Area Neurology
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS, 0.09 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Background publications Chadalavada, Gratton, Bevilacqua: "The human HDV-like CPEB3 ribozyme is intrinsically fast-reacting." in: Biochemistry, Vol. 49, Issue 25, pp. 5321-30, 2010 (PubMed).

Grupe, Li, Rowland et al.: "A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. ..." in: American journal of human genetics, Vol. 78, Issue 1, pp. 78-88, 2005 (PubMed).

Hanna, Kruskal, Ezekowitz et al.: "Role of macrophage oxidative burst in the action of anthrax lethal toxin." in: Molecular medicine (Cambridge, Mass.), Vol. 1, Issue 1, pp. 7-18, 1996 (PubMed).

Catalog No. ABIN951678

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