CUB and Zona Pellucida-Like Domains 1 (CUZD1) (C-Term), (AA 586-614) antibody

Details for Product No. ABIN951734
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Antigen
Synonyms Erg-1, Itmap1, Uo-44, Usg, Utczp, ERG1, UO-44, Uo, ERG-1
Epitope
C-Term, AA 586-614
(2), (2), (2), (1), (1), (1)
Reactivity
Human
(7), (3), (1)
Host
Rabbit
(10), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (2)
Application
Immunocytochemistry (ICC), Immunofluorescence (IF), ELISA, Western Blotting (WB)
(11), (6), (6), (6), (5), (5), (3), (1)
Pubmed 5 references available
Catalog no. ABIN951734
Quantity 0.4 mL
Price
357.50 $   Plus shipping costs $45.00
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Immunogen KLH conjugated synthetic peptide between 586-614 amino acids from the C-terminal region of human CUZD1
Specificity This antibody reacts to CUZD1.
Purification Affinity chromatography on Protein A
Alternative Name CUZD1
Background Potent and specific cellular inhibitor of CaM-kinase II (CAMK2). Traps Ca(2+)/calmodulin on CAMK2. May play an important role in the regulation of cell growth when overexpressed in colon adenocarcinoma LoVo cells. Traps Ca(2+)/calmodulin on CAMK2.
Alternate names: CUB and ZP domain-containing protein 1, CUB and zona pellucida-like domain-containing protein 1
Gene ID 50624
NCBI Accession NP_071317
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS 0.09% (w/v) sodium azide
Preservative Sodium azide
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Clark, Gurney, Abaya et al.: "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment...." in: Genome research, Vol. 13, Issue 10, pp. 2265-70, 2003 (PubMed).

Deloukas, Earthrowl, Grafham et al.: "The DNA sequence and comparative analysis of human chromosome 10...." in: Nature, Vol. 429, Issue 6990, pp. 375-81, 2004 (PubMed).

Leong, Ng, Ong et al.: "Molecular cloning, characterization and isolation of novel spliced variants of the human ortholog of a rat estrogen-regulated membrane-associated protein, UO-44." in: Oncogene, Vol. 23, Issue 33, pp. 5707-18, 2004 (PubMed).

Blanchetot, Chagnon, Dubé et al.: "Substrate-trapping techniques in the identification of cellular PTP targets." in: Methods (San Diego, Calif.), Vol. 35, Issue 1, pp. 44-53, 2004 (PubMed).

Leong, Ong, Tay et al.: "Silencing expression of UO-44 (CUZD1) using small interfering RNA sensitizes human ovarian cancer cells to cisplatin in vitro." in: Oncogene, Vol. 26, Issue 6, pp. 870-80, 2007 (PubMed).

Hosts (10), (1)
Reactivities (7), (3), (1)
Applications (11), (6), (6), (6), (5), (5), (3), (1)
Conjugates (2), (2)
Epitopes (2), (2), (2), (1), (1), (1)
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