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Cyclin C antibody (CCNC) (N-Term)

Details for Product anti-CCNC Antibody No. ABIN951753, Supplier: Log in to see
Antigen
  • CG1C_DROME
  • CG7281
  • CYCC
  • Cln3
  • Cyc-C
  • DmcycC
  • Dmel\\CG7281
  • SRB11
  • cycC
  • cyclinC
  • dTRAP33
  • fj11d06
  • wu:fj11d06
  • zgc:73078
  • Cyclin-C
  • CycC
  • AI451004
  • AU020987
  • CG1C
  • Cyclin C
  • cyclin C
  • g1/s-specific cyclin c
  • CycC
  • ccnc
  • CCNC
  • Ccnc
  • AaeL_AAEL013397
Alternatives
anti-Human Cyclin C antibody for Immunocytochemistry
Epitope
N-Term, AA 1-30
15
10
9
9
6
5
4
4
3
2
2
1
1
1
1
Reactivity
Human
71
48
47
8
5
5
4
4
4
2
2
2
Host
Rabbit
69
2
Clonality
Polyclonal
Conjugate
This Cyclin C antibody is un-conjugated
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Western Blotting (WB)
53
24
16
14
13
11
8
5
2
2
1
1
1
Options
Supplier
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Immunogen KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human CCNC
Isotype Ig
Specificity This antibody reacts to CCNC.
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Saturated Ammonium Sulfate (SAS) precipitation
Alternative Name Cyclin C (CCNC Antibody Abstract)
Background The protein encoded by this gene is a member of the cyclin family of proteins. The encoded protein interacts with cyclin-dependent kinase 8 and induces the phophorylation of the carboxy-terminal domain of the large subunit of RNA polymerase II. The level of mRNAs for this gene peaks in the G1 phase of the cell cycle. Two transcript variants encoding different isoforms have been found for this gene.Synonyms: CCNC, Cyclin-C, SRB11 homolog, hSRB11
Molecular Weight 33243 Da
Gene ID 892
NCBI Accession NP_005181
Research Area Chromatin and Nuclear Signaling, Cell Cycle
Pathways Cell Division Cycle, Regulation of Lipid Metabolism by PPARalpha
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS, 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Flow Cytometry (FACS) image for anti-Cyclin C antibody (CCNC) (N-Term) (ABIN951753) CCNC Antibody (N-term) flow cytometric analysis of Hela cells (right histogram)...
Western Blotting (WB) image for anti-Cyclin C antibody (CCNC) (N-Term) (ABIN951753) CCNC Antibody (N-term) western blot analysis in NCI-H460 cell line lysates (35µ...
Background publications Miyata, Liu, Jankovic, Sashida, Lee, Shieh, Naoe, Moore, Nimer: "Cyclin C regulates human hematopoietic stem/progenitor cell quiescence." in: Stem cells (Dayton, Ohio), Vol. 28, Issue 2, pp. 308-17, 2010 (PubMed).

Makkonen, Malinen, Ropponen, Väisänen, Carlberg: "Cell cycle regulatory effects of retinoic Acid and forskolin are mediated by the cyclin C gene." in: Journal of molecular biology, Vol. 393, Issue 2, pp. 261-71, 2009 (PubMed).

Matsuoka, Ballif, Smogorzewska, McDonald, Hurov, Luo, Bakalarski, Zhao, Solimini, Lerenthal, Shiloh, Gygi, Elledge: "ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage." in: Science (New York, N.Y.), Vol. 316, Issue 5828, pp. 1160-6, 2007 (PubMed).

Katona, Loyer, Roby, Lahti: "Two isoforms of the human cyclin C gene are expressed differentially suggesting that they may have distinct functions." in: Acta biologica Hungarica, Vol. 58, Issue 1, pp. 133-7, 2007 (PubMed).

Lamesch, Li, Milstein, Fan, Hao, Szabo, Hu, Venkatesan, Bethel, Martin, Rogers, Lawlor, McLaren, Dricot, Borick, Cusick, Vandenhaute, Dunham, Hill, Vidal: "hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes." in: Genomics, Vol. 89, Issue 3, pp. 307-15, 2007 (PubMed).