Keratin 75 antibody (N-Term)

Catalog No. ABIN951826

Product Details anti-Keratin 75 Antibody

Target: Keratin 75 (KRT75)

Binding Specificity: AA 65-92, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Keratin 75 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody reacts to KRT75.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 65-92 amino acids from the N-terminal region of human KRT75

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Keratin 75

Target: Keratin 75 (KRT75)

Alternative Name: Cytokeratin 75 (KRT75 Products)

Synonyms: KRT75 antibody, K6HF antibody, KB18 antibody, PFB antibody, 4732468K03Rik antibody, AA589387 antibody, K6hf antibody, Krt2-6hf antibody, Krtcap1 antibody, Kb18 antibody, keratin 75 antibody, keratin, type II cytoskeletal 75 antibody, keratin, type II cytoskeletal 6A antibody, KRT75 antibody, LOC466991 antibody, LOC100566287 antibody, Krt75 antibody

Background: This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. This gene is expressed in the companion layer, upper germinative matrix region of the hair follicle, and medulla of the hair shaft. The encoded protein plays an essential role in hair and nail formation. Variations in this gene have been associated with the hair disorders pseudofolliculitis barbae (PFB) and loose anagen hair syndrome (LAHS).Synonyms: CK75, Cytokeratin-75, K6HF, K75, KB18, KRT75, Keratin, Keratin-6 hair follicle, Keratin-75, Type II keratin-K6hf, type II cytoskeletal 75

Molecular Weight: 59560 Da

Gene ID: 9119

NCBI Accession: NP_004684