DAZ4 antibody (Middle Region)

Catalog No. ABIN951840

Product Details anti-DAZ4 Antibody

Target: DAZ4 (Deleted In Azoospermia 4 (DAZ4))

Binding Specificity: AA 89-120, Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DAZ4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes Human DAZ4 (Center).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 89-120 amino acids from the Central region of Human DAZ4. Genename: DAZ4

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for DAZ4

Target: DAZ4 (Deleted In Azoospermia 4 (DAZ4))

Alternative Name: DAZ4 (DAZ4 Products)

Synonyms: pDP1680 antibody, pDP1681 antibody, DAZ4 antibody, deleted in azoospermia 4 antibody, DAZ4 antibody

Background: This gene is a member of the DAZ gene family and is a candidate for the human Y-chromosomal azoospermia factor (AZF). Its expression is restricted to premeiotic germ cells, particularly in spermatogonia. It encodes an RNA-binding protein that is important for spermatogenesis. Four copies of this gene are found on chromosome Y within palindromic duplications, one pair of genes is part of the P2 palindrome and the second pair is part of the P1 palindrome. Each gene contains a 2.4 kb repeat including a 72-bp exon, called the DAZ repeat, the number of DAZ repeats is variable and there are several variations in the sequence of the DAZ repeat. Each copy of the gene also contains a 10.8 kb region that may be amplified, this region includes five exons that encode an RNA recognition motif (RRM) domain. This gene contains two copies of the 10.8 kb repeat. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq].Synonyms: Deleted in azoospermia protein 4

Molecular Weight: 64785 Da

Gene ID: 57135

NCBI Accession: NP_001005375