Differentially Expressed in FDCP 6 Homolog (Mouse) (DEF6) (C-Term), (AA 499-528) antibody

Details for Product No. ABIN951875
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Antigen
Synonyms DEF6, Def6, zgc:63721, ibp, slat, swap70l, MGC68775, 2410003F05Rik, 6430538D02Rik, AV094905, Ibp, Slat, Slat2, Slat6, IBP, SLAT, SWAP70L
Epitope
C-Term, AA 499-528
(12), (7), (4), (2), (2), (1), (1), (1)
Reactivity
Human
(44), (15), (15), (13), (13), (13), (12)
Host
Rabbit
(29), (9), (6)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
ELISA, Western Blotting (WB)
(30), (17), (10), (10), (3), (3), (2), (1), (1), (1)
Pubmed 4 references available
Quantity 0.4 mL
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Catalog No. ABIN951875
357.50 $
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Immunogen KLH conjugated synthetic peptide between 499-528 amino acids from the C-terminal region of human DEF6
Specificity This antibody recognizes Human DEF6 (C-term).
Purification Affinity Chromatography on Protein A
Alternative Name DEF6
Background DEF6, or IBP, is a guanine nucleotide exchange factor (GEF) for RAC (MIM 602048) and CDC42 (MIM 116952) that is highly expressed in B and T cells (Gupta et al., 2003 [PubMed 12923183]).
Alternate names: DEF-6, Differentially expressed in FDCP 6 homolog, IBP, IRF4-binding protein, SLAT, SWAP70L
Molecular Weight 73910 Da
Gene ID 50619
NCBI Accession NP_071330
Research Area Signaling
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS 0.09% Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Rajaraman, Brenner, Butler et al.: "Common variation in genes related to innate immunity and risk of adult glioma." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 18, Issue 5, pp. 1651-8, 2009 (PubMed).

Rajaraman, Brenner, Neta et al.: "Risk of meningioma and common variation in genes related to innate immunity." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 19, Issue 5, pp. 1356-61, 2010 (PubMed).

Han, Lan, Park et al.: "Polymorphisms in innate immunity genes and risk of childhood leukemia." in: Human immunology, Vol. 71, Issue 7, pp. 727-30, 2010 (PubMed).

Zhao, Li, Bradfield et al.: "The role of height-associated loci identified in genome wide association studies in the determination of pediatric stature." in: BMC medical genetics, Vol. 11, pp. 96, 2010 (PubMed).

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