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Dematin antibody (Middle Region)
EPB49
Reactivity: Human
WB, EIA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-Dematin Antibody
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Target
See all Dematin (EPB49) Antibodies
Dematin (EPB49)
(erythrocyte Membrane Protein Band 4.9 (Dematin) (EPB49))
Binding Specificity
All epitopes for Dematin antibodies
AA 248-277, Middle Region
Reactivity
All reactivities for Dematin antibodies
Human
Host
All hosts for Dematin antibodies
Rabbit
Clonality
All clonalities for Dematin antibodies
Polyclonal
Conjugate
All conjugates for Dematin antibodies
This Dematin antibody is un-conjugated
Application
All applications for Dematin antibodies
Western Blotting (WB), Enzyme Immunoassay (EIA)
Specificity
This antibody recognizes Human Dematin (Center).
Purification
Affinity Chromatography on Protein A
Immunogen
KLH conjugated synthetic peptide between 248-277 amino acids from the Central region of Human Dematin. Genename: EPB49
Isotype
Ig Fraction
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
0.25 mg/mL
Buffer
PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for Dematin
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Target
Dematin (EPB49)
(erythrocyte Membrane Protein Band 4.9 (Dematin) (EPB49))
Alternative Name
Dematin (EPB49 Products )
Synonyms
MGC80597 antibody, MGC108072 antibody, EPB49 antibody, DMT antibody, AI325486 antibody, Epb4.9 antibody, Epb49 antibody, dematin antibody, dematin actin binding protein L homeolog antibody, dematin actin binding protein antibody, dmtn.L antibody, DMTN antibody, dmtn antibody, Dmtn antibody
Background
Dematin, or EPB49, is an actin-bundling protein originally identified in the erythroid membrane skeleton. Its actin-bundling activity is abolished upon phosphorylation by cAMP-dependent protein kinase and is restored after dephosphorylation (Rana et al., 1993 [PubMed 8341682]).Synonyms: DMT, EPB49, Erythrocyte membrane protein band 4.9
Molecular Weight
45514 Da
Gene ID
2039
NCBI Accession
NP_001107607
Pathways
Regulation of Actin Filament Polymerization
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