Receptor-Interacting Serine-threonine Kinase 4 (RIPK4) (AA 513-542), (Middle Region) antibody

Details for Product No. ABIN951913
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Synonyms dik, pkk, rip4, ankk2, ankrd3, ripk4a, MGC53701, MGC132134, zgc:55705, wu:fj80b10, ripk4b, RIPK4, ANKK2, ANKRD3, DIK, NKRD3, PKK, PPS2, RIP4, 2310069J12Rik, AI552420, Ankrd3, DIk
AA 513-542, Middle Region
(18), (16), (14), (5), (3), (2), (2), (1), (1), (1)
Human, Mouse (Murine)
(52), (8), (3), (1)
(39), (9), (4)
(4), (4), (4), (4), (4), (4)
Enzyme Immunoassay (EIA), Western Blotting (WB)
(48), (33), (16), (7), (6), (2), (2), (1)
Pubmed 3 references available
Quantity 0.4 mL
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Catalog No. ABIN951913
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Immunogen KLH conjugated synthetic peptide between 513-542 amino acids from the Central region of Human RIPK4 Genename: dik
Isotype Ig
Specificity This antibody recognizes Human and Mouse RIPK4 (Center).
Purification Affinity Chromatography on Protein A
Alternative Name RIPK4
Background DIK is a serine/threonine protein kinase that interacts with protein kinase C-delta. The encoded protein can also activate NFkappaB and is required for keratinocyte differentiation. This kinase undergoes autophosphorylation.Synonyms: ANKRD3, Ankyrin repeat domain-containing protein 3, DIK, PKC-delta-interacting protein kinase, Receptor-interacting serine/threonine-protein kinase 4
Molecular Weight 86408 Da
Gene ID 54101
NCBI Accession NP_065690
Research Area Signaling
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS, 0.09 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Background publications Adams, Munz: "RIP4 is a target of multiple signal transduction pathways in keratinocytes: implications for epidermal differentiation and cutaneous wound repair." in: Experimental cell research, Vol. 316, Issue 1, pp. 126-37, 2009 (PubMed).

Lee, Wei, Tsai-Wu et al.: "Novel PKC signaling is required for LPS-induced soluble Flt-1 expression in macrophages." in: Journal of leukocyte biology, Vol. 84, Issue 3, pp. 835-41, 2008 (PubMed).

Kim, Oleksyn, Rossi et al.: "Protein kinase C-associated kinase is required for NF-kappaB signaling and survival in diffuse large B-cell lymphoma cells." in: Blood, Vol. 111, Issue 3, pp. 1644-53, 2008 (PubMed).

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