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DNALI1 antibody (Dynein, Axonemal, Light Intermediate Chain 1) (C-Term)

Details for Product anti-DNALI1 Antibody No. ABIN951953, Supplier: Log in to see
Antigen
  • 1700023A09Rik
  • AW049135
  • dJ423B22.5
  • hp28
  • P28
  • zgc:171493
  • zgc:171595
Epitope
C-Term, AA 214-243
20
15
8
5
5
2
1
Reactivity
Human
52
11
11
2
2
1
1
Host
Rabbit
45
7
Clonality
Polyclonal
Conjugate
This DNALI1 antibody is un-conjugated
2
2
2
2
2
2
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
46
23
7
6
5
3
2
Supplier
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Immunogen conjugated synthetic peptide between 214-243 amino acids from the C-terminal region of Human DNALI1.
Isotype Ig
Specificity This antibody recognizes Human DNALI1 (C-term).
Purification Affinity Chromatography on Protein A
Alternative Name DNALI1 (DNALI1 Antibody Abstract)
Background This gene is the human homolog of the Chlamydomonas inner dynein arm gene, p28. The precise function of this gene is not known, however, it is a potential candidate for immotile cilia syndrome (ICS). Ultrastructural defects of the inner dynein arms are seen in patients with ICS. Immotile mutant strains of Chlamydomonas, a biflagellated algae, exhibit similar defects.Synonyms: Axonemal dynein light intermediate polypeptide 1, HP28, Inner dynein arm light chain axonemal
Molecular Weight 29662 Da
Gene ID 7802
NCBI Accession NP_003453
Research Area Signaling, Cytoskeleton
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-DNALI1 antibody (Dynein, Axonemal, Light Intermediate Chain 1) (C-Term) (ABIN951953) Western blot analysis of DNALI1 Antibody (C-term) in T47D cell line lysates (35ug/lan...
Background publications Combs, Kim, Tan, Ligon, Holzbaur, Kuhn, Poenie: "Recruitment of dynein to the Jurkat immunological synapse." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 40, pp. 14883-8, 2006 (PubMed).

Kastury, Taylor, Shen, Arver, Gutierrez, Fisher, Coucke, Van Hauwe, Van Camp, Bhasin: "Complementary deoxyribonucleic acid cloning and characterization of a putative human axonemal dynein light chain gene." in: The Journal of clinical endocrinology and metabolism, Vol. 82, Issue 9, pp. 3047-53, 1997 (PubMed).

Hanna, Kruskal, Ezekowitz, Bloom, Collier: "Role of macrophage oxidative burst in the action of anthrax lethal toxin." in: Molecular medicine (Cambridge, Mass.), Vol. 1, Issue 1, pp. 7-18, 1996 (PubMed).