EDEM3 antibody (C-Term)

Catalog No. ABIN952023

Product Details anti-EDEM3 Antibody

Target: EDEM3 (ER Degradation Enhancer, Mannosidase alpha-Like 3 (EDEM3))

Binding Specificity: AA 773-802, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EDEM3 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes Human EDEM3 (C-term).

Purification: Affinity Chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 773-802 amino acids from the C-terminal region of human EDEM3

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for EDEM3

Target: EDEM3 (ER Degradation Enhancer, Mannosidase alpha-Like 3 (EDEM3))

Alternative Name: EDEM3 (EDEM3 Products)

Synonyms: RGD1561496 antibody, C1orf22 antibody, 2310050N11Rik antibody, ER degradation enhancing alpha-mannosidase like protein 3 antibody, ER degradation enhancer, mannosidase alpha-like 3 L homeolog antibody, ER degradation enhancer, mannosidase alpha-like 3 antibody, Edem3 antibody, EDEM3 antibody, edem3.L antibody, edem3 antibody

Background: Quality control in the endoplasmic reticulum (ER) ensures that only properly folded proteins are retained in the cell through recognition and degradation of misfolded or unassembled proteins. EDEM3 belongs to a group of proteins that accelerate degradation of misfolded glycoproteins in the ER (Hirao et al., 2006 [PubMed 16431915]).Synonyms: C1orf22, ER degradation-enhancing alpha-mannosidase-like 3

Molecular Weight: 104664 Da

Gene ID: 80267

NCBI Accession: NP_079467

Pathways: SARS-CoV-2 Protein Interactome