EIF3C antibody (N-Term)

Catalog No. ABIN952048

Product Details anti-EIF3C Antibody

Target: EIF3C (Eukaryotic Translation Initiation Factor 3 Subunit C (EIF3C))

Binding Specificity: AA 126-155, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EIF3C antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: This antibody recognizes EIF3CL (N-term).

Cross-Reactivity (Details): Species reactivity (expected):Bovine, Mouse, Rat.
Species reactivity (tested):Human.

Purification: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 126-155 amino acids from the N-terminal region of human EIF3CL

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for EIF3C

Target: EIF3C (Eukaryotic Translation Initiation Factor 3 Subunit C (EIF3C))

Alternative Name: EIF3C / EIF3S8 (EIF3C Products)

Synonyms: eif3s8 antibody, fi37c04 antibody, zgc:66128 antibody, wu:fb34a08 antibody, wu:fi37c04 antibody, EIF3S8 antibody, EIF3CL antibody, eif3-p110 antibody, LOC733086 antibody, eIF3c antibody, eIF3-S8 antibody, AO090011000340 antibody, eIF3-p110 antibody, 110kDa antibody, 3230401O13Rik antibody, Eif3s8 antibody, NIPIL(A3) antibody, NipilA3 antibody, Xs antibody, Xsl antibody, EIF3C antibody, eukaryotic translation initiation factor 3, subunit C antibody, eukaryotic translation initiation factor 3 subunit C antibody, eukaryotic translation initiation factor 3 subunit 8 antibody, Eukaryotic translation initiation factor 3 subunit C antibody, translation initiation factor eIF3c antibody, translation initiation factor eIF-3 subunit 8 antibody, eukaryotic translation initiation factor 3 subunit C L homeolog antibody, eukaryotic translation initiation factor 3, subunit C-like antibody, eif3c antibody, LOC454016 antibody, LOC479795 antibody, EIF3C antibody, Smp_000480 antibody, eIF3c antibody, ANI_1_1094124 antibody, AOR_1_578054 antibody, PTRG_08272 antibody, SJAG_04981 antibody, TERG_03202 antibody, PGTG_09255 antibody, Tsp_05110 antibody, Eif3c antibody, eif3c.L antibody, EIF3CL antibody, eif-3.C antibody

Background: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.Synonyms: Eukaryotic translation initiation factor 3 subunit 8, Eukaryotic translation initiation factor 3 subunit C, eIF3 p110

Molecular Weight: 105344 Da

Gene ID: 8663

NCBI Accession: NP_001032897

Pathways: Ribonucleoprotein Complex Subunit Organization