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Elongation Factor RNA Polymerase II (ELL) (AA 523-553), (C-Term) antibody

Details for Product No. ABIN952063, Supplier: Log in to see
Antigen
  • C19orf17
  • Ell1
  • ELL1
  • MEN
  • Men
  • PPP1R68
  • wu:fc60b11
  • zgc:63836
Epitope
C-Term, AA 523-553
34
31
4
4
3
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine)
91
37
15
2
2
1
1
Host
Rabbit
83
8
Clonality
Polyclonal
Conjugate
Un-conjugated
5
5
5
4
4
4
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
69
44
17
11
5
3
3
2
1
Supplier
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Immunogen Synthetic peptide - KLH conjugated - corresponding to the C-terminal region (between 523-553aa) of human ELL.
Isotype Ig
Specificity This antibody detects ELL at C-term.
Cross-Reactivity (Details) Species reactivity (tested):Human, Mouse
Purification Purified through a protein A column; followed by peptide affinity purification.
Alternative Name ELL (ELL Antibody Abstract)
Background Synonyms: C19orf17, Eleven-nineteen lysine-rich leukemia protein, RNA polymerase II elongation factor ELL
Gene ID 8178
NCBI Accession NP_006523
Research Area Chromatin and Nuclear Signaling, Transcription Factors
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) Sodium Azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-Elongation Factor RNA Polymerase II (ELL) (AA 523-553), (C-Term) antibody (ABIN952063) Western blot analysis in A549 cell line lysates (35ug/lane) using ELL  Antibody (C-te...
Western Blotting (WB) image for anti-Elongation Factor RNA Polymerase II (ELL) (AA 523-553), (C-Term) antibody (ABIN952063) Western blot analysis in mouse lung tissue lysates (35ug/lane) using ELL  Antibody (C...
Background publications Liu, Ai, Xiao, Liu, Wang, Xin, He, Guo, Wang: "ELL is an HIF-1alpha partner that regulates and responds to hypoxia response in PC3 cells." in: The Prostate, Vol. 70, Issue 7, pp. 797-805, 2010 (PubMed).

Zhou, Feng, Ban, Liu, Wang, Xiao: "Elongation factor ELL (Eleven-Nineteen Lysine-rich Leukemia) acts as a transcription factor for direct thrombospondin-1 regulation." in: The Journal of biological chemistry, Vol. 284, Issue 28, pp. 19142-52, 2009 (PubMed).

Jiang, Ai, Xiao, Wang: "FB1, an E2A fusion partner in childhood leukemia, interacts with U19/EAF2 and inhibits its transcriptional activity." in: Cancer letters, Vol. 253, Issue 2, pp. 265-72, 2007 (PubMed).

Matsuoka, Ballif, Smogorzewska, McDonald, Hurov, Luo, Bakalarski, Zhao, Solimini, Lerenthal, Shiloh, Gygi, Elledge: "ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage." in: Science (New York, N.Y.), Vol. 316, Issue 5828, pp. 1160-6, 2007 (PubMed).