You are viewing an incomplete version of our website. Please click to reload the website as full version.

EPO antibody (Erythropoietin) (N-Term)

Details for Product anti-EPO Antibody No. ABIN952117, Supplier: Log in to see
Antigen
  • EP
  • EPO
  • MVCD2
Alternatives
anti-Human EPO antibody for Western Blotting
Epitope
N-Term, AA 19-48
20
18
15
13
13
10
8
5
5
5
5
3
3
3
3
3
2
2
1
1
1
1
Reactivity
Human, Mouse (Murine)
242
51
31
5
2
1
1
Host
Rabbit
163
100
4
3
3
1
Clonality
Polyclonal
Conjugate
This EPO antibody is un-conjugated
23
17
12
6
6
6
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
194
168
19
15
11
10
9
7
7
6
5
4
3
3
3
2
2
1
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

It's quick and easy to submit your validation proposal. I want to validate this product

Learn more

Available images

Immunogen KLH conjugated synthetic peptide between 19-48 amino acids from the N-terminal region of Human Erythropoietin. Genename: EPO
Isotype Ig
Specificity This antibody recognizes Human and Mouse Erythropoietin / EPO (N-term).
Purification Affinity Chromatography on Protein A
Alternative Name Erythropoietin / EPO (EPO Antibody Abstract)
Background EPO is a member of the EPO/TPO family and encodes a secreted, glycosylated cytokine composed of four alpha helical bundles. The protein is found in the plasma and regulates red cell production by promoting erythroid differentiation and initiating hemoglobin synthesis. This protein also has neuroprotective activity against a variety of potential brain injuries and antiapoptotic functions in several tissue types. [provided by RefSeq].Synonyms: Epoetin
Molecular Weight 21307 Da
Gene ID 2056
NCBI Accession NP_000790
Pathways JAK-STAT Signaling
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-EPO antibody (Erythropoietin) (N-Term) (ABIN952117) Western blot analysis of Erythropoietin / EPO Antibody (N-term) in K562 cell line lys...
Western Blotting (WB) image for anti-EPO antibody (Erythropoietin) (N-Term) (ABIN952117) Western blot analysis of Erythropoietin / EPO Antibody (N-term) in mouse L929 cell li...
Background publications Kristensen, Pedersen-Bjergaard, Schalkwijk, Olsen, Thorsteinsson: "Erythropoietin and vascular endothelial growth factor as risk markers for severe hypoglycaemia in type 1 diabetes." in: European journal of endocrinology / European Federation of Endocrine Societies, Vol. 163, Issue 3, pp. 391-8, 2010

Kim, Cho, Huh, Kim: "Transduction of human EPO into human bone marrow mesenchymal stromal cells synergistically enhances cell-protective and migratory effects." in: Molekuliarnaia biologiia, Vol. 44, Issue 4, pp. 656-63, 2010

Carraway, Suliman, Jones, Chen, Babiker, Piantadosi: "Erythropoietin activates mitochondrial biogenesis and couples red cell mass to mitochondrial mass in the heart." in: Circulation research, Vol. 106, Issue 11, pp. 1722-30, 2010

Shi, Hodges, Dunlop, Percy, Maxwell, El-Tanani, Lappin: "Erythropoietin-induced activation of the JAK2/STAT5, PI3K/Akt, and Ras/ERK pathways promotes malignant cell behavior in a modified breast cancer cell line." in: Molecular cancer research : MCR, Vol. 8, Issue 4, pp. 615-26, 2010

Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010