EPO antibody (Erythropoietin) (N-Term)

Details for Product anti-EPO Antibody No. ABIN952117, Supplier: Log in to see
Antigen
  • EPO
  • EP
  • MVCD2
  • erythropoietin
  • EPO
  • epo
  • Epo
Alternatives
anti-Human EPO antibody for Western Blotting
Epitope
N-Term, AA 19-48
19
15
14
14
13
13
7
6
6
5
5
3
3
3
3
3
2
2
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine)
339
75
43
7
4
3
3
2
2
1
1
1
1
1
1
Host
Rabbit
192
171
15
5
3
1
Clonality
Polyclonal
Conjugate
This EPO antibody is un-conjugated
28
21
16
10
6
6
6
5
5
5
5
5
5
5
5
4
4
4
4
3
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
249
216
67
60
57
51
30
13
10
10
7
6
4
3
2
2
2
2
2
1
1
Options
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Immunogen KLH conjugated synthetic peptide between 19-48 amino acids from the N-terminal region of Human Erythropoietin. Genename: EPO
Isotype Ig
Specificity This antibody recognizes Human and Mouse Erythropoietin / EPO (N-term).
Purification Affinity Chromatography on Protein A
Alternative Name Erythropoietin / EPO (EPO Antibody Abstract)
Background EPO is a member of the EPO/TPO family and encodes a secreted, glycosylated cytokine composed of four alpha helical bundles. The protein is found in the plasma and regulates red cell production by promoting erythroid differentiation and initiating hemoglobin synthesis. This protein also has neuroprotective activity against a variety of potential brain injuries and antiapoptotic functions in several tissue types. [provided by RefSeq].Synonyms: Epoetin
Molecular Weight 21307 Da
Gene ID 2056
NCBI Accession NP_000790
Pathways JAK-STAT Signaling, Hormone Activity, Negative Regulation of intrinsic apoptotic Signaling, Negative Regulation of Transporter Activity
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-Erythropoietin (EPO) (AA 19-48), (N-Term) antibody (ABIN952117) Western blot analysis of Erythropoietin / EPO Antibody (N-term) in K562 cell line lys...
Western Blotting (WB) image for anti-Erythropoietin (EPO) (AA 19-48), (N-Term) antibody (ABIN952117) Western blot analysis of Erythropoietin / EPO Antibody (N-term) in mouse L929 cell li...
Background publications Kristensen, Pedersen-Bjergaard, Schalkwijk, Olsen, Thorsteinsson: "Erythropoietin and vascular endothelial growth factor as risk markers for severe hypoglycaemia in type 1 diabetes." in: European journal of endocrinology / European Federation of Endocrine Societies, Vol. 163, Issue 3, pp. 391-8, 2010 (PubMed).

Kim, Cho, Huh, Kim: "Transduction of human EPO into human bone marrow mesenchymal stromal cells synergistically enhances cell-protective and migratory effects." in: Molekuliarnaia biologiia, Vol. 44, Issue 4, pp. 656-63, 2010 (PubMed).

Carraway, Suliman, Jones, Chen, Babiker, Piantadosi: "Erythropoietin activates mitochondrial biogenesis and couples red cell mass to mitochondrial mass in the heart." in: Circulation research, Vol. 106, Issue 11, pp. 1722-30, 2010 (PubMed).

Shi, Hodges, Dunlop, Percy, Maxwell, El-Tanani, Lappin: "Erythropoietin-induced activation of the JAK2/STAT5, PI3K/Akt, and Ras/ERK pathways promotes malignant cell behavior in a modified breast cancer cell line." in: Molecular cancer research : MCR, Vol. 8, Issue 4, pp. 615-26, 2010 (PubMed).

Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010 (PubMed).

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