ERI2 antibody (Middle Region)

Catalog No. ABIN952142

Product Details anti-ERI2 Antibody

Target: ERI2 (EXOD1) (ERI1 Exoribonuclease Family Member 2 (EXOD1))

Binding Specificity: AA 443-472, Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ERI2 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes Human EXOD1 (Center).

Purification: Affinity Chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 443-472 amino acids from the Central region of Human EXOD1 Genename: ERI2

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for ERI2

Target: ERI2 (EXOD1) (ERI1 Exoribonuclease Family Member 2 (EXOD1))

Alternative Name: EXOD1 (EXOD1 Products)

Synonyms: exod1 antibody, EXOD1 antibody, Exod1 antibody, 4933424N09Rik antibody, mKIAA1504 antibody, eri2 antibody, ERI1 exoribonuclease family member 2 L homeolog antibody, ERI1 exoribonuclease family member 2 antibody, exoribonuclease 2 antibody, eri2.L antibody, ERI2 antibody, Eri2 antibody, eri2 antibody

Background: EXOD1 (Exonuclease domain-containing protein 1), also known as ERI2 (ERI1 exoribonuclease 2), is a 691 amino acid protein that contains one exonuclease domain, which catalyzes the hydrolysis of unpaired or mismatched nucleotides. EXOD1 acitivity is dependent on the binding of two magnesium ions per subunit. There are four isoforms of EXOD1 that are produced as a result of alternative splicing events. The gene encoding EXOD1 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3 % of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.Synonyms: Exonuclease domain-containing protein 1, KIAA1504, MGC16943

Molecular Weight: 77401 Da

Gene ID: 112479

NCBI Accession: NP_001136197