Fatty Acid Desaturase 2 (FADS2) (N-Term), (AA 78-108) antibody

Details for Product No. ABIN952158
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Antigen
Synonyms Fadsd6, DRD5/D6, wu:fb64c04, wu:fb69e08, zgc:112502, 2900042M13Rik, Fadsd2, D6D, DES6, FADSD6, LLCDL2, SLL0262, TU13
Epitope
N-Term, AA 78-108
(10), (7), (7), (2), (2), (1)
Reactivity
Human
(32), (15), (12), (12), (12), (12)
Host
Rabbit
(33)
Clonality
Polyclonal
Conjugate
Un-conjugated
(3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(24), (19), (14), (10), (9), (4), (3)
Pubmed 2 references available
Quantity 0.4 mL
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Catalog No. ABIN952158
357.50 $
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Immunogen KLH conjugated synthetic peptide between 78-108 amino acids from the N-terminal region of Human FADS2
Isotype Ig
Specificity This antibody recognizes FADS2 (N-term).
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Protein A Chromatoghraphy followed by peptide affinity purification
Alternative Name FADS2
Background The protein encoded by this gene is a member of the fatty acid desaturase (FADS) gene family. Desaturase enzymes regulate unsaturation of fatty acids through the introduction of double bonds between defined carbons of the fatty acyl chain. FADS family members are considered fusion products composed of an N-terminal cytochrome b5-like domain and a C-terminal multiple membrane-spanning desaturase portion, both of which are characterized by conserved histidine motifs. This gene is clustered with family members FADS1 and FADS2 at 11q12-q13.1, this cluster is thought to have arisen evolutionarily from gene duplication based on its similar exon/intron organization.Synonyms: D6D, Delta 6 desaturase, Delta(6) fatty acid desaturase, Fatty acid desaturase 2
Gene ID 9415
NCBI Accession NP_004256
Research Area Cardiovascular, Fatty Acids, Metabolism
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS, 0.09 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Background publications Mathias, Vergara, Gao et al.: "FADS genetic variants and omega-6 polyunsaturated fatty acid metabolism in a homogeneous island population." in: Journal of lipid research, Vol. 51, Issue 9, pp. 2766-74, 2010 (PubMed).

Bailey, Xie, Do et al.: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010 (PubMed).

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