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Fanconi Anemia, Complementation Group C (FANCC) (AA 529-558), (C-Term) antibody

Details for Product No. ABIN952264, Supplier: Log in to see
Antigen
  • zgc:154105
  • FANCC
  • fa3
  • fac
  • facc
  • FA3
  • FAC
  • FACC
  • BB116513
  • Facc
Epitope
AA 529-558, C-Term
30
15
7
6
5
4
3
2
2
2
2
2
1
1
1
Reactivity
Human
96
20
14
3
2
1
Host
Rabbit
81
16
Clonality
Polyclonal
Conjugate
Un-conjugated
4
4
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
79
38
32
32
19
15
12
11
6
3
2
1
1
1
Supplier
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Immunogen KLH conjugated synthetic peptide between 529~558 amino acids from the C-terminal region of human FANCC
Isotype Ig
Specificity This antibody recognizes Human FANCC (C-term).
Purification Affinity Chromatography on Protein A
Alternative Name FANCC (FANCC Antibody Abstract)
Background The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity, they are related by their assembly into a common nuclear protein complex. This protein is for complementation group C.Synonyms: FAC, FACC, Fanconi anemia group C protein
Molecular Weight 63429 Da
Gene ID 2176
NCBI Accession NP_000127
Research Area Chromatin and Nuclear Signaling, DNA/RNA
Pathways
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Flow Cytometry (FACS) image for anti-Fanconi Anemia, Complementation Group C (FANCC) (AA 529-558), (C-Term) antibody (ABIN952264) Flow cytometric analysis of HL-60 cells using FANCC Antibody (C-term) Cat.-No AP51608...
Immunofluorescence (IF) image for anti-Fanconi Anemia, Complementation Group C (FANCC) (AA 529-558), (C-Term) antibody (ABIN952264) Confocal immunofluorescent analysis of FANCC Antibody (C-term) Cat.-No AP51608PU-N wi...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Fanconi Anemia, Complementation Group C (FANCC) (AA 529-558), (C-Term) antibody (ABIN952264) Formalin fixed and paraffin embedded testis tissue reacted with FANCC Antibody (C-ter...
Western Blotting (WB) image for anti-Fanconi Anemia, Complementation Group C (FANCC) (AA 529-558), (C-Term) antibody (ABIN952264) Western blot analysis of FANCC Antibody (C-term) in HL-60,HepG2 cell line lysates (35...
Background publications McWilliams, Bamlet, de Andrade et al.: "Polymorphic variants in hereditary pancreatic cancer genes are not associated with pancreatic cancer risk." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 18, Issue 9, pp. 2549-52, 2009 (PubMed).

Barroso, Pita, Arias et al.: "The Fanconi anemia family of genes and its correlation with breast cancer susceptibility and breast cancer features." in: Breast cancer research and treatment, Vol. 118, Issue 3, pp. 655-60, 2009 (PubMed).

Michiels, Laplanche, Boulet et al.: "Genetic polymorphisms in 85 DNA repair genes and bladder cancer risk." in: Carcinogenesis, Vol. 30, Issue 5, pp. 763-8, 2009 (PubMed).

Palmieri, Wilson, Iversen et al.: "Polymorphism in the IL18 gene and epithelial ovarian cancer in non-Hispanic white women. ..." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 17, Issue 12, pp. 3567-72, 2008 (PubMed).