FOLR2 antibody (N-Term)

Catalog No. ABIN952352

Product Details anti-FOLR2 Antibody

Target: FOLR2 (Folate Receptor 2 (Fetal) (FOLR2))

Binding Specificity: AA 16-44, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FOLR2 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes Human Folate receptor beta (N-term).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 16-44 amino acids from the N-terminal region of Human Folate receptor beta Genename: FOLR2

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for FOLR2

Target: FOLR2 (Folate Receptor 2 (Fetal) (FOLR2))

Alternative Name: Folate Receptor beta (FOLR2 Products)

Synonyms: FOLR2 antibody, BETA-HFR antibody, FBP antibody, FBP/PL-1 antibody, FR-BETA antibody, FR-P3 antibody, FBP2 antibody, Folbp-2 antibody, Folbp2 antibody, folate receptor 1 antibody, folate receptor beta antibody, folate receptor 2 (fetal) antibody, FOLR1 antibody, FOLR2 antibody, Folr2 antibody

Background: The protein encoded by this gene is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68 % and 79 % sequence homology with the FOLR1 and FOLR3 proteins, respectively. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients. Multiple transcript variants that encode the same protein have been found for this gene.Synonyms: FOLR2, FR-beta, Folate receptor 2, Placental folate-binding protein

Molecular Weight: 29280 Da

Gene ID: 2350

NCBI Accession: NP_001107008

Pathways: Dicarboxylic Acid Transport