Folate Receptor 2 (Fetal) (FOLR2) (N-Term), (AA 16-44) antibody

Details for Product No. ABIN952352
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Antigen
Synonyms FBP2, FR-P3, Folbp2, Folbp-2, BETA-HFR, FBP, FBP/PL-1, FR-BETA, FOLR2
Epitope
N-Term, AA 16-44
(4), (2), (2), (1), (1), (1), (1), (1)
Reactivity
Human
(25), (14), (12)
Host
Rabbit
(21), (3), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
ELISA, Western Blotting (WB)
(15), (10), (8), (3), (2), (1), (1)
Pubmed 2 references available
Catalog no. ABIN952352
Quantity 0.4 mL
Price
357.50 $   Plus shipping costs $45.00
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen KLH conjugated synthetic peptide between 16-44 amino acids from the N-terminal region of Human Folate receptor beta Genename: FOLR2
Specificity This antibody recognizes Human Folate receptor beta (N-term).
Purification Protein A column, followed by peptide affinity purification
Alternative Name Folate receptor beta
Background The protein encoded by this gene is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68% and 79% sequence homology with the FOLR1 and FOLR3 proteins, respectively. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients. Multiple transcript variants that encode the same protein have been found for this gene.
Alternate names: FOLR2, FR-beta, Folate receptor 2, Placental folate-binding protein
Molecular Weight 29280 Da
Gene ID 2350
NCBI Accession NP_001107008.1
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09% (w/v) Sodium Azide as preservative
Preservative Sodium azide
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Bailey, Xie, Do et al.: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010 (PubMed).

OByrne, Au, Morrison et al.: "Association of folate receptor (FOLR1, FOLR2, FOLR3) and reduced folate carrier (SLC19A1) genes with meningomyelocele." in: Birth defects research. Part A, Clinical and molecular teratology, Vol. 88, Issue 8, pp. 689-94, 2010 (PubMed).

Hosts (21), (3), (1)
Reactivities (25), (14), (12)
Applications (15), (10), (8), (3), (2), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (4), (2), (2), (1), (1), (1), (1), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
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