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Fucosyltransferase 6 (Alpha (1,3) Fucosyltransferase) (FUT6) (N-Term), (AA 19-49) antibody

Details for Product No. ABIN952400
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Antigen
Synonyms FUT6, fut356, ATFUT6, F7A19.16, F7A19_16, fucosyltransferase 6, FCT3A, FT1A, Fuc-TVI, FucT-VI
Epitope
N-Term, AA 19-49
(7), (7), (6), (6), (2), (1), (1)
Reactivity
Human
(35), (1), (1), (1), (1), (1), (1)
Host
Rabbit
(35), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Western Blotting (WB)
(27), (15), (13), (10), (7), (5), (1)
Pubmed 5 references available
Quantity 0.4 mL
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days
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The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN952400
357.50 $
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Immunogen KLH conjugated synthetic peptide between 19-49 amino acids from the N-terminal region of Human Fucosyltransferase 6 Genename: FUT6
Specificity This antibody recognizes Human Fucosyltransferase 6 (N-term).
Purification Protein A column, followed by peptide affinity purification
Alternative Name Fucosyltransferase 6
Background The protein encoded by this gene is a Golgi stack membrane protein that is involved in the creation of sialyl-Lewis X, an E-selectin ligand. Mutations in this gene are a cause of fucosyltransferase-6 deficiency. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq].
Alternate names: 3)-fucosyltransferase, Alpha-(1, FCT3A, FUT6, FucT-VI, Fucosyltransferase VI, Galactoside 3-L-fucosyltransferase
Molecular Weight 41860 Da
Gene ID 2528
NCBI Accession NP_000141
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09% (w/v) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Higai, Miyazaki, Azuma et al.: "Transcriptional regulation of the fucosyltransferase VI gene in hepatocellular carcinoma cells." in: Glycoconjugate journal, Vol. 25, Issue 3, pp. 225-35, 2008 (PubMed).

Nordén, Nyström, Olofsson: "Activation of host antiviral RNA-sensing factors necessary for herpes simplex virus type 1-activated transcription of host cell fucosyltransferase genes FUT3, FUT5, and FUT6 and subsequent expression of sLe(x) in virus-infected cells." in: Glycobiology, Vol. 19, Issue 7, pp. 776-88, 2009 (PubMed).

Talmud, Drenos, Shah et al.: "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip." in: American journal of human genetics, Vol. 85, Issue 5, pp. 628-42, 2009 (PubMed).

Stern, Padilla, Wagner et al.: "Development of immunohistochemistry assays to assess GALNT14 and FUT3/6 in clinical trials of dulanermin and drozitumab." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 16, Issue 5, pp. 1587-96, 2010 (PubMed).

Bailey, Xie, Do et al.: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010 (PubMed).

Validation Images
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