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Details for Product No. ABIN952425

Growth Arrest and DNA-Damage-Inducible, gamma (GADD45G) (N-Term), (AA 1-30) antibody

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Antigen
Synonyms CR6, DDIT2, GRP17, GADD45gamma, OIG37, C86281, AI327420, zgc:77806, GADD45G, XGadd45-gamma, cr6, ddit2, gadd45gamma, grp17, xgadd45g
Epitope
»Alternatives N-Term, AA 1-30
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives ELISA, Western Blotting (WB)
Pubmed 5 references available
Catalog no. ABIN952425
Quantity 0.4 mL
Price
346.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 6 to 8 Business Days
Immunogen KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human GADD45G
Specificity This antibody recognizes Human GADD45G (N-term).
Purification Protein A column, followed by peptide affinity purification
Alternative Name GADD45G
Background This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The GADD45G is highly expressed in placenta.
Alternate names: CR6, Cytokine-responsive protein CR6, DDIT2, DNA-damage-inducible transcript 2, Growth arrest and DNA-damage-inducible protein GADD45 gamma
Molecular Weight 17121 Da
Gene ID 10912
NCBI Accession NP_006696
Research Area DNA/RNA, Apoptosis/Necrosis
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09% (w/v) Sodium Azide as preservative
Preservative Sodium azide
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Zhu, Shao, Xu et al.: "Gadd45-alpha and Gadd45-gamma utilize p38 and JNK signaling pathways to induce cell cycle G2/M arrest in Hep-G2 hepatoma cells." in: Molecular biology reports, Vol. 36, Issue 8, pp. 2075-85, 2009 (PubMed).

Palmieri, Wilson, Iversen et al.: "Polymorphism in the IL18 gene and epithelial ovarian cancer in non-Hispanic white women." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 17, Issue 12, pp. 3567-72, 2008 (PubMed).

Yu, Cho, Park et al.: "Urinary GADD45gamma expression is associated with progression of lgA nephropathy." in: American journal of nephrology, Vol. 30, Issue 2, pp. 135-9, 2009 (PubMed).

Zhang, Li, Shao et al.: "Semi-quantitative detection of GADD45-gamma methylation levels in gastric, colorectal and pancreatic cancers using methylation-sensitive high-resolution melting analysis." in: Journal of cancer research and clinical oncology, Vol. 136, Issue 8, pp. 1267-73, 2010 (PubMed).

Flores, Burnstein: "GADD45gamma: a new vitamin D-regulated gene that is antiproliferative in prostate cancer cells." in: Endocrinology, Vol. 151, Issue 10, pp. 4654-64, 2010 (PubMed).

Alternatives for antigen "Growth Arrest and DNA-Damage-Inducible, gamma (GADD45G)", type "Antibodies"
Hosts (23), (20), (9), (1)
Reactivities (51), (15), (14), (11), (11), (11), (1)
Applications (37), (15), (9), (8), (7), (2), (2), (1), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (3), (3), (3), (2), (2), (2), (1), (1), (1), (1)
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