GALR3 antibody (Galanin Receptor 3) (C-Term)

Details for Product anti-GALR3 Antibody No. ABIN952454, Supplier: Log in to see
Antigen
  • GALR3
  • Galnr3
  • galanin receptor 3
  • GALR3
  • LOC100037699
  • LOC100220568
  • LOC100355009
  • Galr3
Alternatives
anti-Human GALR3 antibody for ELISA
Epitope
C-Term, AA 278-307
37
14
4
2
2
2
2
1
1
1
1
1
Reactivity
Human
77
23
22
2
2
2
1
Host
Rabbit
60
19
Clonality
Polyclonal
Conjugate
This GALR3 antibody is un-conjugated
4
4
4
3
3
3
1
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
41
39
23
17
13
5
1
1
Options
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Immunogen KLH conjugated synthetic peptide between 278-307 amino acids from the C-terminal region of human GALR3
Isotype Ig
Specificity This antibody recognizes Human GATLR3 (C-term).
Purification Protein A column, followed by peptide affinity purification
Alternative Name GALR3 (GALR3 Antibody Abstract)
Background The neuropeptide galanin modulates a variety of physiologic processes including cognition/memory, sensory/pain processing, hormone secretion, and feeding behavior. The human galanin receptors are G protein-coupled receptors that functionally couple to their intracellular effector through distinct signaling pathways. GALR3 is found in many tissues and may be expressed as 1.4-, 2.4-, and 5-kb transcriptsSynonyms: GAL3-R, GALNR3, Galanin receptor type 3
Molecular Weight 39573 Da
Gene ID 8484
NCBI Accession NP_003605
Research Area Neurology
Pathways cAMP Metabolic Process, Feeding Behaviour
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-GALR3 antibody (Galanin Receptor 3) (C-Term) (ABIN952454) Western blot analysis of GALR3 Antibody (C-term) in Hela cell line lysates (35ug/lane...
Background publications Shimada, Miyagawa, Kawashima, Tanaka, Honda, Honda, Tokunaga: "An approach based on a genome-wide association study reveals candidate loci for narcolepsy." in: Human genetics, Vol. 128, Issue 4, pp. 433-41, 2010 (PubMed).

Saus, Brunet, Armengol, Alonso, Crespo, Fernández-Aranda, Guitart, Martín-Santos, Menchón, Navinés, Soria, Torrens, Urretavizcaya, Vallès, Gratacòs, Estivill: "Comprehensive copy number variant (CNV) analysis of neuronal pathways genes in psychiatric disorders identifies rare variants within patients." in: Journal of psychiatric research, Vol. 44, Issue 14, pp. 971-8, 2010 (PubMed).

Gratacòs, Costas, de Cid, Bayés, González, Baca-García, de Diego, Fernández-Aranda, Fernández-Piqueras, Guitart, Martín-Santos, Martorell, Menchón, Roca, Sáiz-Ruiz, Sanjuán, Torrens, Urretavizcaya et al.: "Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and ..." in: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, Vol. 150B, Issue 6, pp. 808-16, 2009 (PubMed).

Belfer, Hipp, Bollettino, McKnight, Evans, Virkkunen, Albaugh, Max, Goldman, Enoch: "Alcoholism is associated with GALR3 but not two other galanin receptor genes." in: Genes, brain, and behavior, Vol. 6, Issue 5, pp. 473-81, 2007 (PubMed).

Berger, Tuechler, Almer, Kogner, Ratschek, Kerbl, Iismaa, Jones, Sperl, Kofler: "Elevated expression of galanin receptors in childhood neuroblastic tumors." in: Neuroendocrinology, Vol. 75, Issue 2, pp. 130-8, 2002 (PubMed).