GGTLC2 antibody (Middle Region)

Catalog No. ABIN952511

Product Details anti-GGTLC2 Antibody

Target: GGTLC2 (gamma-Glutamyltransferase Light Chain 2 (GGTLC2))

Binding Specificity: AA 140-169, Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GGTLC2 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes Human GGTLC2 (Center).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 140-169 amino acids from the Central region of human GGTLC2

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for GGTLC2

Target: GGTLC2 (gamma-Glutamyltransferase Light Chain 2 (GGTLC2))

Alternative Name: GGTLC2 (GGTLC2 Products)

Synonyms: GGTL4 antibody, gamma-glutamyltransferase light chain 2 antibody, GGTLC2 antibody

Background: Gamma-glutamyltransferase-1 (GGT1, MIM 612346) is a membrane-bound extracellular enzyme that cleaves gamma-glutamyl peptide bonds in glutathione and other peptides and transfers the gamma-glutamyl moiety to acceptors. Autocatalytic cleavage of the GGT1 precursor polypeptide produces a heavy chain and a light chain that associate with each other to form the functional enzyme. Light chain-only GGTs, such as GGTLC2, contain a region corresponding to the GGT1 light chain, but they lack the membrane-anchoring heavy chain region (Heisterkamp et al., 2008 [PubMed 18357469]).[supplied by OMIM].Synonyms: GGTL4, Gamma-glutamyltransferase light chain 2

Molecular Weight: 23661 Da

Gene ID: 91227

NCBI Accession: NP_954578