Heparanase 2 antibody (C-Term)

Catalog No. ABIN952713

Product Details anti-Heparanase 2 Antibody

Target: Heparanase 2 (HPSE2)

Binding Specificity: AA 450-480, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Heparanase 2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes Human Heparanase-2 / HPA2 (C-term).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 450-480 amino acids from the C-terminal region of human Heparanase-2 / HPA2 Genename: HPSE2

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Heparanase 2

Target: Heparanase 2 (HPSE2)

Alternative Name: Heparanase-2 / HPA2 (HPSE2 Products)

Background: Endoglycosidase which is a cell surface and extracellular matrix-degrading enzyme. Cleaves heparan sulfate proteoglycans (HSPGs) into heparan sulfate side chains and core proteoglycans. Also implicated in the extravasation of leukocytes and tumor cell lines. Due to its contribution to metastasis and angiogenesis, it is considered to be a potential target for anti-cancer therapies.Synonyms: HPSE2

Molecular Weight: 66596 Da

Gene ID: 60495

NCBI Accession: NP_001159716

Pathways: Glycosaminoglycan Metabolic Process