EPAS1 antibody (N-Term)
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- Target See all EPAS1 Antibodies
- EPAS1 (Endothelial PAS Domain Protein 1 (EPAS1))
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Binding Specificity
- AA 127-154, N-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This EPAS1 antibody is un-conjugated
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Application
- Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)
- Specificity
- This antibody recognizes Human HIF2A / HIF2 alpha (N-term).
- Purification
- Affinity Chromatography on Protein A
- Immunogen
- KLH conjugated synthetic peptide between 127-154 amino acids from the N-terminal region of Human HIF2A Genename: EPAS1
- Isotype
- Ig Fraction
- Top Product
- Discover our top product EPAS1 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- EPAS1 (Endothelial PAS Domain Protein 1 (EPAS1))
- Alternative Name
- HIF2A / HIF2 alpha (EPAS1 Products)
- Synonyms
- EPAS1 antibody, ECYT4 antibody, HIF2A antibody, HLF antibody, MOP2 antibody, PASD2 antibody, bHLHe73 antibody, HIF-2alpha antibody, HRF antibody, Hif2a antibody, bhlhe73 antibody, ecyt4 antibody, hif2 antibody, hif2a antibody, hif2alpha antibody, hlf antibody, mop2 antibody, pasd2 antibody, EPAS antibody, EPAS-1 antibody, endothelial PAS domain protein 1 antibody, endothelial PAS domain protein 1 L homeolog antibody, EPAS1 antibody, epas1 antibody, Epas1 antibody, epas1.L antibody
- Background
- This gene encodes a transcription factor involved in the induction of genes regulated by oxygen, which is induced as oxygen levels fall. The encoded protein contains a basic-helix-loop-helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels. Mutations in this gene are associated with erythrocytosis familial type 4.Synonyms: BHLHE73, Basic-helix-loop-helix-PAS protein MOP2, Class E basic helix-loop-helix protein 73, EPAS1, Endothelial PAS domain-containing protein 1, HIF-1 alpha-like factor, HIF-2 alpha, HIF-related factor, HLF, Hypoxia-inducible factor 2 alpha, MOP2, PASD2
- Molecular Weight
- 96459 Da
- Gene ID
- 2034
- NCBI Accession
- NP_001421
- Pathways
- Signaling Events mediated by VEGFR1 and VEGFR2, Warburg Effect
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