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Homeodomain Interacting Protein Kinase 1 (HIPK1) (AA 892-922), (C-Term) antibody

Details for Product No. ABIN952740, Supplier: Log in to see
Antigen
  • HIPK1
  • myak
  • nbak2
  • hipk1
  • Myak
  • Nbak2
  • 1110062K04Rik
Epitope
AA 892-922, C-Term
17
15
15
10
6
2
2
1
1
Reactivity
Human
52
5
3
1
1
Host
Rabbit
30
24
Clonality
Polyclonal
Conjugate
Un-conjugated
2
2
2
2
2
2
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
39
31
22
9
8
2
1
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Immunogen KLH conjugated synthetic peptide between 892-922 amino acids from the C-terminal region of human HIPK1
Isotype Ig
Specificity This antibody recognizes Human HIPK1 (C-term).
Purification Protein A column, followed by peptide affinity purification
Alternative Name HIPK1 (HIPK1 Antibody Abstract)
Background The protein encoded by this gene belongs to the Ser/Thr family of protein kinases and HIPK subfamily. It phosphorylates homeodomain transcription factors and may also function as a co-repressor for homeodomain transcription factors. Alternative splicing results in four transcript variants encoding four distinct isoforms.Synonyms: Homeodomain-interacting protein kinase 1, KIAA0630
Molecular Weight 130843 Da
Gene ID 204851
NCBI Accession NP_689909
Research Area Chromatin and Nuclear Signaling, Transcription Factors
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Homeodomain Interacting Protein Kinase 1 (HIPK1) (AA 892-922), (C-Term) antibody (ABIN952740) Immunohistochemistry analysis in formalin fixed and paraffin embedded human breast ca...
Western Blotting (WB) image for anti-Homeodomain Interacting Protein Kinase 1 (HIPK1) (AA 892-922), (C-Term) antibody (ABIN952740) Western blot analysis of HIPK1 Antibody (C-term) Cat.-No AP52049PU-N pre-incubated wi...
Background publications Matre, Nordgård, Alm-Kristiansen et al.: "HIPK1 interacts with c-Myb and modulates its activity through phosphorylation." in: Biochemical and biophysical research communications, Vol. 388, Issue 1, pp. 150-4, 2009 (PubMed).

Li, Zhang, Luo et al.: "Tumor necrosis factor alpha-induced desumoylation and cytoplasmic translocation of homeodomain-interacting protein kinase 1 are critical for apoptosis signal-regulating kinase 1-JNK/p38 activation." in: The Journal of biological chemistry, Vol. 280, Issue 15, pp. 15061-70, 2005 (PubMed).

Rush, Moritz, Lee et al.: "Immunoaffinity profiling of tyrosine phosphorylation in cancer cells." in: Nature biotechnology, Vol. 23, Issue 1, pp. 94-101, 2005 (PubMed).

Colland, Jacq, Trouplin et al.: "Functional proteomics mapping of a human signaling pathway." in: Genome research, Vol. 14, Issue 7, pp. 1324-32, 2004 (PubMed).

Song, Lee: "Role of the ASK1-SEK1-JNK1-HIPK1 signal in Daxx trafficking and ASK1 oligomerization." in: The Journal of biological chemistry, Vol. 278, Issue 47, pp. 47245-52, 2003 (PubMed).