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HMGCL antibody (Middle Region)
HMGCL
Reactivity: Human
WB, EIA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-HMGCL Antibody
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Target
See all HMGCL Antibodies
HMGCL
(3-Hydroxymethyl-3-Methylglutaryl-CoA Lyase (HMGCL))
Binding Specificity
All epitopes for HMGCL antibodies
AA 160-190, Middle Region
Reactivity
All reactivities for HMGCL antibodies
Human
Host
All hosts for HMGCL antibodies
Rabbit
Clonality
All clonalities for HMGCL antibodies
Polyclonal
Conjugate
All conjugates for HMGCL antibodies
This HMGCL antibody is un-conjugated
Application
All applications for HMGCL antibodies
Western Blotting (WB), Enzyme Immunoassay (EIA)
Specificity
This antibody recognizes Human HMG-CoA lyase / HMGCL (Center).
Purification
Protein A column, followed by peptide affinity purification
Immunogen
KLH conjugated synthetic peptide between 160-190 amino acids from the Central region of human HMG-CoA lyase / HMGCL
Isotype
Ig Fraction
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Discover our top product HMGCL Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
0.25 mg/mL
Buffer
PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for HMGCL
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Target
HMGCL
(3-Hydroxymethyl-3-Methylglutaryl-CoA Lyase (HMGCL))
Alternative Name
HMG-CoA Lyase / HMGCL (HMGCL Products )
Synonyms
Afu7g01720 antibody, AO090038000541 antibody, AW476067 antibody, HL antibody, zgc:56248 antibody, 3-hydroxymethyl-3-methylglutaryl-CoA lyase S homeolog antibody, 3-hydroxymethyl-3-methylglutaryl-CoA lyase antibody, 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase antibody, 3-hydroxy-3-methylglutaryl-Coenzyme A lyase antibody, hmgcl.S antibody, HMGCL antibody, AFUA_7G01720 antibody, NFIA_114450 antibody, ACLA_065820 antibody, AOR_1_910074 antibody, PMAA_004600 antibody, TSTA_103060 antibody, ARB_04874 antibody, TRV_06573 antibody, Hmgcl antibody, hmgcl antibody
Background
HMGCL belongs to the HMG-CoA lyase family. It is a mitochondrial enzyme that catalyzes the final step of leucine degradation and plays a key role in ketone body formation. Mutations in this gene are associated with HMG-CoA lyase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].Synonyms: mitochondrial Hydroxymethylglutaryl-CoA lyase
Molecular Weight
34360 Da
Gene ID
3155
NCBI Accession
NP_000182
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