HMGN3 antibody (N-Term)

Catalog No. ABIN952763

Product Details anti-HMGN3 Antibody

Target: HMGN3 (High Mobility Group Nucleosomal Binding Domain 3 (HMGN3))

Binding Specificity: AA 1-30, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HMGN3 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes Human HMGN3 / TRIP7 (N-term).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human HMGN3 / TRIP7

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for HMGN3

Target: HMGN3 (High Mobility Group Nucleosomal Binding Domain 3 (HMGN3))

Alternative Name: HMGN3 / TRIP7 (HMGN3 Products)

Synonyms: Trip7 antibody, PNAS-25 antibody, TRIP7 antibody, 1110002A15Rik antibody, 6330514M13Rik antibody, BB071015 antibody, high mobility group nucleosomal binding domain 3 L homeolog antibody, high mobility group nucleosomal binding domain 3 antibody, hmgn3.L antibody, HMGN3 antibody, Hmgn3 antibody

Background: Thyroid hormone receptors are hormone-dependent transcription factors that regulate expression of a variety of specific target genes. The protein encoded by this gene binds thyroid hormone receptor beta, but only in the presence of thyroid hormone. The encoded protein, a member of the HMGN protein family, is thought to reduce the compactness of the chromatin fiber in nucleosomes, thereby enhancing transcription from chromatin templates. Two transcript variants encoding different isoforms have been found for this gene.Synonyms: High mobility group nucleosome-binding domain-containing protein 3, PNAS-24, TR-interacting protein 7, Thyroid receptor-interacting protein 7

Molecular Weight: 10666 Da

Gene ID: 9324

NCBI Accession: NP_001188291