HYAL1 antibody (C-Term)

Catalog No. ABIN952807

Product Details anti-HYAL1 Antibody

Target: HYAL1 (Hyaluronidase-1 (HYAL1))

Binding Specificity: AA 279-309, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HYAL1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes Human HYAL1 / Hyaluronidase-1 (C-term).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 279-309 amino acids from the C-terminal region of Human HYAL1 / Hyaluronidase-1

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for HYAL1

Target: HYAL1 (Hyaluronidase-1 (HYAL1))

Alternative Name: HYAL1 / Hyaluronidase-1 (HYAL1 Products)

Synonyms: HYAL-1 antibody, LUCA1 antibody, NAT6 antibody, Hya1 antibody, Hyal-1 antibody, hyaluronoglucosaminidase 1 antibody, HYAL1 antibody, Hyal1 antibody

Background: This gene encodes a lysosomal hyaluronidase. Hyaluronidases intracellularly degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan is thought to be involved in cell proliferation, migration and differentiation. This enzyme is active at an acidic pH and is the major hyaluronidase in plasma. Mutations in this gene are associated with mucopolysaccharidosis type IX, or hyaluronidase deficiency. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. Multiple transcript variants encoding different isoforms have been found for this gene.Synonyms: Hyal-1, Hyaluronoglucosaminidase-1, LUCA1, Lung carcinoma protein 1

Molecular Weight: 48368 Da

Gene ID: 3373

NCBI Accession: NP_695013

Pathways: Glycosaminoglycan Metabolic Process