Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

Mouse anti-Human IgG (Fd Region) Antibody

WB, FACS, EIA Monoclonal HP6045 IgG1 unconjugated
Catalog No. ABIN952843
  • Target See all IgG products
    IgG
    Binding Specificity
    • 2356
    • 502
    • 411
    • 188
    • 130
    • 123
    • 94
    • 29
    • 28
    • 28
    • 17
    • 8
    • 6
    • 6
    • 6
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Fd Region
    Reactivity
    • 697
    • 679
    • 568
    • 452
    • 368
    • 239
    • 200
    • 148
    • 140
    • 132
    • 122
    • 98
    • 96
    • 95
    • 94
    • 63
    • 46
    • 33
    • 27
    • 16
    • 12
    • 10
    • 8
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 1727
    • 1486
    • 537
    • 215
    • 118
    • 103
    • 33
    • 31
    • 21
    • 17
    • 15
    • 11
    • 11
    • 1
    Mouse
    Clonality
    • 3354
    • 192
    • 1
    Monoclonal
    Application
    • 1867
    • 1788
    • 1784
    • 1534
    • 988
    • 934
    • 913
    • 515
    • 234
    • 115
    • 115
    • 110
    • 100
    • 87
    • 77
    • 50
    • 50
    • 48
    • 32
    • 27
    • 25
    • 21
    • 17
    • 16
    • 11
    • 8
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)
    Cross-Reactivity (Details)
    Species reactivity (tested):Human.
    Purification
    Protein G Chromatography.
    Immunogen
    Human IgG Fd
    Clone
    HP6045
    Isotype
    IgG1
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    PBS containing 0.02 % Sodium Azide as preservative.
    Preservative
    Sodium azide
    Precaution of Use
    WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -28 °C for longer.
  • Lebozec, Jandrot-Perrus, Avenard, Favre-Bulle, Billiald: "Design, development and characterization of ACT017, a humanized Fab that blocks platelet's glycoprotein VI function without causing bleeding risks." in: mAbs, Vol. 9, Issue 6, pp. 945-958, (2017) (PubMed).

  • Target
    IgG
    Abstract
    IgG Products
    Target Type
    Antibody
    Background
    The Fd region of Human Immunoglobulins is located at the N-terminal part of the heavy chain and is an essential component of the antigen-binding fragment Fab. Fd, like the light chain, contains a C-terminal constant (CH1) and N- terminal variable (VH) domain. The hypervariable regions in both the light chain and Fd determine the specificity of the Fab.Synonyms: Human Immunoglobulin G
You are here:
Support