INPP5B antibody (C-Term)

Catalog No. ABIN952906

Product Details anti-INPP5B Antibody

Target: INPP5B (Inositol Polyphosphate-5-Phosphatase, 75kDa (INPP5B))

Binding Specificity: AA 957-987, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This INPP5B antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes Human INPP5B / 5PTase 2 (C-term).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 957-987 amino acids from the C-terminal region of Human INPP5B / 5PTase 2.

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for INPP5B

Target: INPP5B (Inositol Polyphosphate-5-Phosphatase, 75kDa (INPP5B))

Abstract: INPP5B Products

Synonyms: 75kDa antibody, AW260155 antibody, INPP5P antibody, 5PTase antibody, inositol polyphosphate-5-phosphatase B antibody, type II inositol 1,4,5-trisphosphate 5-phosphatase-like antibody, inositol polyphosphate-5-phosphatase B L homeolog antibody, inositol polyphosphate 5-phosphatase OCRL-1 antibody, INPP5B antibody, LOC100224437 antibody, inpp5b.L antibody, LOC100159919 antibody, Inpp5b antibody

Background: Cellular calcium signaling is controlled by the production of inositol phosphates (IPs) by phospholipase C in response to extracellular signals. The IP signaling molecules are inactivated by a family of inositol polyphosphate-5-phosphatases (5-phosphatases). INPP5B encodes the type II 5-phosphatase. The protein is localized to the cytosol and mitochondria, and associates with membranes through an isoprenyl modification near the C-terminus. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq].Synonyms: 4, 5-trisphosphate 5-phosphatase, 75 kDa inositol polyphosphate-5-phosphatase, Phosphoinositide 5-phosphatase, Type II inositol-1

Molecular Weight: 112852 Da

Gene ID: 3633

NCBI Accession: NP_005531