KAT2A antibody (C-Term)

Catalog No. ABIN952987

Product Details anti-KAT2A Antibody

Target: KAT2A (K(lysine) Acetyltransferase 2A (KAT2A))

Binding Specificity: AA 806-837, C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KAT2A antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes Human and Mouse KAT2A / GCN5L2 (C-term).

Purification: Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS

Immunogen: KLH conjugated synthetic peptide between 806-837 amino acids from the C-terminal region of Human KAT2A / GCN5L2

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for KAT2A

Target: KAT2A (K(lysine) Acetyltransferase 2A (KAT2A))

Alternative Name: KAT2A / GCN5L2 (KAT2A Products)

Synonyms: KAT2A antibody, GCN5L2 antibody, GCN5 antibody, PCAF-b antibody, hGCN5 antibody, 1110051E14Rik antibody, AW212720 antibody, Gcn5 antibody, Gcn5l2 antibody, mmGCN5 antibody, K(lysine) acetyltransferase 2A antibody, lysine acetyltransferase 2A antibody, histone acetyltransferase KAT2A antibody, ras-related protein Rab-5C antibody, KAT2A antibody, LOC100176452 antibody, LOC100597293 antibody, Kat2a antibody

Background: KAT2A, or GCN5, is a histone acetyltransferase (HAT) that functions primarily as a transcriptional activator. It also functions as a repressor of NF-kappa-B (see MIM 164011) by promoting ubiquitination of the NF-kappa-B subunit RELA (MIM 164014) in a HAT-independent manner (Mao et al., 2009 [PubMed 19339690]).Synonyms: General control of amino acid synthesis protein 5-like 2, HGCN5, Histone acetyltransferase GCN5, Histone acetyltransferase KAT2A, HsGCN5, Lysine acetyltransferase 2A, STAF97

Molecular Weight: 93926 Da

Gene ID: 2648

NCBI Accession: NP_066564

Pathways: Chromatin Binding, Tube Formation